radiaton

[Granica4818]

Yester was my husband's first day of 5 radiation treatments through next Friday. Targeted area mastitis to the T9 of the spine and rib. Crossing our fingers this gets it. He has not yet been put on any other meds. Is this normal? The will then wait 2 weeks and get a PSA test and I think then he will get his first PSMA pet scan. Does that sound right?

[mrscruffy]

After my first radiation treatment I opted for no medication. didn't work and went on the meds. That was 6 1/2 years ago. Just had another tumor pop up on T4 so 5 Days 2 weeks ago. Not doing meds was my choice

[Tall_Allen]

It sounds backwards. Usually the PSMA PET scan identifies the metastases to be treated with radiation. He should be started on Lupron immediately. It is much more important than the radiation.

[GMAN2667 in reply to Tall_Allen]

oncologist said all CT scans showed no cancer but 1 spot on spine- and if radiation kills it and psa goes to undetectable after 2 weeks - no need to start lupron and xtandi - psa is still only .8 now -but has been doubling last 3 months--to .8 -----( this is Husband , ) thx for all your input - very very helpful **** u know your stuff - and i know i am at the beginning of all this - PSMAPETSCAN was denied after they found cancer on spine- was already to go - had appt and all--

[Tall_Allen in reply to GMAN2667]

It is almost certain that PSA will be undetectable, but that is only because the PSA was treated instead of the cancer.

prostatecancer.news/2020/07...

[GMAN2667 in reply to Tall_Allen]

will read this tonight - VERY informative - Toledo Clinic and Cleveland clinic have me doing this way - frustrating ! appreciate *

[anony2020 in reply to GMAN2667]

It seems what TA and the article are saying is that RT may killed the cancer that is detectable, ie 4mm or bigger. It does not kill all the cells. Some cancer is still there building more cancer. So you need ADT etc to kill the rest. Is that right, TA?

[Justfor_ in reply to GMAN2667]

PSA has a half life of 3-3.5 days. Even if your latest 0.8 doesn't get any higher in the interim period, two weeks of pure decay (zero new addition while this) can only brink it down to 0.05-0.03, still detectable.

[Davhmit]

I am also a Gleeson 9 5+4 very rare,

he needs to go on Lupron ASAP

[Brysonal]

My treatment started with SBRT when I went to oligometastatic but my PSMA PET scan was first (picked up a met to 3rd rib and also T1). My RO said SBRT at this stage can trigger the abscopal effect in 30% of people so we gave it ago. My PSMA PET scan definitely came first.

It didn't work for me as further skeletal bone mets were popping up all over a few months later although it worked on those two. I started systemic treatment December 2021.

I am now NED with a clear scan and mets resolved as of two weeks ago. PSA undetectable for 5 months. Now having a cancer vaccine under a clinical trial to try to boost my immune response for when it fights back!