177Lu-PSMA clinical trials for chemo naive patients

[meowlicious99]

We are in India and I know ppl here have been getting lu pre chemo.

My MO offers 177Lu-PSMA therapy too, however he has suggested we get chemo first and then lu if required.

(case details in my profile)

He mentioned that it has only been trialed in that sequence and not on chemo naive patients.

Wondering if there are any trials that have reported results so far on lu for chemo naive patients

Only ones i know so far are

1. SPLASH clinicaltrials.gov/ct2/show... , no results posted. Data from its lead-in phase, however, are anticipated to be made available before Q1 2023

[Tall_Allen]

There are several ongoing trials in the US.

[tango65]

This study may be of interest to you:

ncbi.nlm.nih.gov/pmc/articl...

[Ramp7]

I am chemo naive, and have just completed a Trial Study at Dana Farber with Novartis LuPSMA177. It was casually mentioned that Novartis would like to expand into this direction, pre Chemo.