My MO has not been a fan, but recently he agreed to try with me. He started me out on a .025 weekly estradoil patch. Nothing. He agreed to move me up to .05 mg change patch twice a week. Nothing. Coming ot an end. I had 2, .025 mg patches left over so i used the leftover .025mg weekly patch with the twice weekly .05mg giving me.075. Nothing. Got one left and will try that but dont expect much. I get about 14 flashes a day and the ones at night cause pain in my lower legs for a mnute before the heat bomb explodes. Is .075 a reasonable dose or is a .1 the minimum.
Any comments will be appreciated.
Joe
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Joeym1040
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I’ve been using 0.1 patches twice a week for several years now. I used to get intense hot flashes on an hourly basis, I counted 15 one day. 0.1 works like a charm, I rarely get a hot flash now and if I do it is typically mild.
ED...I used to get them every 45 minutes like clockwork! Thatt was in 2011. And some were very, very bad. Now down to about 15 a day and less serious except at night.I will try to get the doc to give me the .1 and hope for the best.
I’m not sure what the problem is that your doc has. If he’s afraid of cardiac issues, it’s not a problem with the patch since it’s absorbed by the skin and not the liver. Snuffy Myers originally prescribed them for me, I now see Dr. Sartor and he likes the idea of the patches not only for hot flashes but for bone health as well.
I also use .1 patches. I worked up from .025. My flashes lessened as I increased the dosage. I now have none at all and my mental state is much improved. My MO now tests my testosterone along with my PSA. He now has most of his patients like me on patches. According to him, they are all getting the same results as I get.
.1 twice a week is my dosage. My MO is not concerned with my E2 levels—only my testosterone and its effect on my PSA. He’s trying to keep me alive with an acceptable level of quality to my life.
It is not easy on the psychology or physiology of humans who suddenly have no hormones of any kind in their bodies.
For reference estradiol (E2) is the "active" part of estrogen which includes estrone (E1) and estradiol (E2). If you get your blood checked, be sure to ask for the E2 number specifically.
Reply (1)
Low-dose E2 patches are intended to replace the minimal amount of E2 essential for bone health. Men produce E2 by aromatization of T. ADT can therefore result in E2 defficiency. IMO, the target level for E2 should be 12-20 pg/mL. (Some suggest you can go as high as 30 pg/ml)
E2 is only a threat to male health when >30 pg/mL. Some studies (e.g. cardio) equate the E2:T ratio with risk.
{When massive levels of E2 are used to suppress T, the ratio becomes meaningless.}
I have been using an over-the-counter cream that has allowed me to keep my E2 in the reference range. I still have hot flushes but not as often or as intense.
I have yet to find a doctor that will prescribe E2 patches to me...not SOC!
Northwest Florida.I have been buying it from Amazon.
BioLabs PRO Natural Bioidentical Bi-EST 5.0 Cream For Women, Three Month Supply (3.6 oz - Unscented). The price has gone up since I first purchased it.
I have had my E2, reluctantly included in lab request by my Drs and have purchased lab test from Life Extension to monitor my E2. My range has been anywhere from 8 to 40. The difficulty is in dispensing the same amount of cream each day. Patches would correct that problem, although as noted various strength of the patches were tried.
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