Hi,
My father did CT and blood work, and had an appointment with the doctor who follows him, today.
Unfortunately, despite the CT not showing disease progression, the PSA rise to 300.
My father will immediately stop Xtandi and repeat PSA.
His doctor talked about doing chemotherapy again (10).
Is anything we can do better?
Nothing better, but you can consider adding Provenge.
What chemo is he expected to do now?
Can we have hope that he responds well to other treatments down the road?
I do not know what to think.
If docetaxel no longer works, he can try cabazitaxel (Jevtana). If Pluvicto is available, he can do that.
Looks like my dad might have to do Docetaxel again. Does it usually work?
His illness doesn't seem to respond very well to hormone treatments. :/
He has been experiencing pain in his knee for a month and a half and then fluid accumulation. She removed the fluid but he has been feeling pain in his leg that has been associated with sciatica. The oncologist wants to anticipate the bone scintigraphy to see if it could be from the disease/metastasis.
If it worked throughout all his multiple treatments before, there is every reason to hope it will continue to work.
Is there any Dr. you can recommend in Portugal?
Sorry, I'm not very familiar with any Portuguese doctors. I've seen the name of Nuno Sousa at Instituto Português de Oncologia do Porto Francisco Gentil. Porto. Portugal.
My father is being treated in that hospital, IPO. However, as it is a public hospital, doctors are changing constantly. It has always been women. So the name Nuno Sousa is not familiar to me!Thank you once again.
If he already had chemo he could consider Lu 177 PSMA treatment. He will need a PSMA PET/CT to determine if there are PSMA avid metastases. CT and bone scans are much less sensitive than PSMA PET/CT to detect mets.
Yes, docetaxel in 2020.Thanks tango65. I dont know if it is a possibility in the hospital.
Switch to another ADT drug, i.e. zytiga, amplitude, etc.
Thanks 🙌🏻
Is there any Dr. you can recommend in Portugal?
Sorry, I am in the US.
It has quit for me also.... Starting modified BAT. I've already had many treatments and MO is out of cards to play... Best of luck to you
Can you ask for a liquid biopsy and Nubequa?
I was at my MO this week for a 3 month Lupron shot. One of his patients is enrolled at Dana Farber for a BAT trial. Response so far has been positive. BAT works for some.
I thought that BAT is used for those whose PSA has been low and stable for a period of time.
It is a therapy where they introduce high levels of testosterone for period of time and then lower it. It is repeated sort of like in a sine wave.
B is for bipolar. It means >1 drug that reduces testosterone. And another pox on everyone who's too busy to spell out their acronyms.
how about Lu177
Thanks for your tip.We are looking for anything that can help!
Can you find a clinical trial in Spain, or even better Portugal?
CUF can arrange somatic/genomic tests if you can't get these through the public system. I think you are entitled to access trials in other countries who are part of the EU - you could ask your MO maybe?
What is CUF?
My father has already performed genetic tests at IPO, with negative results.
Do you think that is time for clinical trials?
So, my dad has blood work again, and PSA continues to rise, from 300 to 700. He's going to start docetaxel, again, after having already done it in 2020.Has anyone here taken docetaxel more than once?
Thanks.
Xtandi is Working
Xtandi working
Xtandi while on Chemo is working Well
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