WHY IS XGEVA SO EXPENSIVE?: I have been... - Advanced Prostate...

Advanced Prostate Cancer

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WHY IS XGEVA SO EXPENSIVE?

john4803 profile image
52 Replies

I have been on Xgeva for 3 months & my insurance is being charged $10,635 per month, of which they are paying $10,200. It is a monthly injection.

I talked to a Walgreens Pharmacy employee and he said the cash value of Xgeva is $3,200. Seems like a heck of a markup. Any ideas?

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john4803
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52 Replies
spouse21 profile image
spouse21

Answer: It's because you live in the USA where our government doesn't negotiate much with Big Pharma. Here's what they paid in Canada in 2016 annually:

Denosumab (Xgeva) is available as a 120 mg/1.7mL single-use vial of solution for injection at a cost of $575.55 per vial (Ontario Drug Benefit Exceptional Access Formulary, October 2015).1 At the recommended dose of 120 mg/1.7mL every four weeks, the annual cost of denosumab is $7,482.

ncbi.nlm.nih.gov/books/NBK4...

If I have time, I'll try to research today's comparative costs among the different countries. Five years ago, my husband's Zytiga charge was $11,000 per month, and the rep tried to bully him into agreeing to one more month's worth even though it was failing!

john4803 profile image
john4803 in reply to spouse21

Thanks!

EdBacon profile image
EdBacon in reply to john4803

Another issue is Xgeva does not have a generic. That's part of why it's so expensive.

An equally good substitute is Zometa (an infusion done every 12 weeks). Zometa has a generic (zolendronic acid) and is significantly less expensive.

ncbi.nlm.nih.gov/books/NBK4...

Annual Cost: $2,521 to $3,361

You have to go in for infusions vs a shot, but it's only every 12 weeks.

john4803 profile image
john4803 in reply to EdBacon

My understanding is that you can only get it monthly?

EdBacon profile image
EdBacon in reply to john4803

I got it every 12 weeks when I came in for my ADT shot. They gave it to me for 2 years because after that, there is no proven benefit.

dhccpa profile image
dhccpa in reply to spouse21

I'm not on Zytiga yet, but I found a pharma plan to go with Medicare where I can buy the generic version for $110/120 250-mg pills. If I do the 1 pill daily with food, down to $27/month. But Enzi is not generic, so bad news if I have to take it.

CAMPSOUPS profile image
CAMPSOUPS

I could be way out in left field but question. Do you get the Xgeva injection or infusion at the cancer center ? In house like that usually get better insurance coverage. At any rate your coverage ain't so good.

john4803 profile image
john4803 in reply to CAMPSOUPS

I get it in the Infusion Center but it is a simple shot in the back of the arm. Could be done any where.

Teacherdude72 profile image
Teacherdude72

Try Nubeqa at $12,000 a month. Medicare covers all but $500. My state has a assistance program that pay all but $10.00.

dhccpa profile image
dhccpa in reply to Teacherdude72

Medicare covers my Xgeva quarterly injections 100%.

john4803 profile image
john4803 in reply to dhccpa

I am thinking you are taking Prolia or some other generic because, from my understanding it is only monthly?

dhccpa profile image
dhccpa in reply to john4803

Since it's the injection, I'll have to look at my Medicare site. It is Xgeva or it's generic. I get a shot quarterly.

I see what you mean, though, on the Xgeva site. I'll have to ask my MO. I'm due for a two-year bone density scan in a couple of months.

john4803 profile image
john4803 in reply to Teacherdude72

I pay $555, which I can afford but I don't understand the mark up?

davebliz profile image
davebliz

I'm in Canada and cost is $750 monthly. Drug isn't covered by our National Health Plan. I have private insurance so pay $150 monthly.

Chask profile image
Chask

Fortunately I live in Australia where thanks to our Universal Health Care, Xgeva is prescribed at a cost of A$43 for a months supply, however because I am a Senior, the cost is reduced to A$6.40, and because we have a “safety net” feature which means that after you have expended a certain amount all scrips are free.

john4803 profile image
john4803 in reply to Chask

That is unreal!

Blackpatch profile image
Blackpatch

This forum is predominantly American, and our US colleagues are at least one more Jan 6 event away from recognising that their versions of government and personal freedom make it near impossible for government to negotiate fair pricing for just about anything. A topic best avoided….

PSAed profile image
PSAed in reply to Blackpatch

Too late for me as I've already put "both feet" into it regarding medication costs on another thread. In my defence I made my post in genuine astonishment at the personal costs our US brothers have to pay for similar cancer medications that I get for a nominal amount here in WA. Pity I didn't see your post beforehand!

anonymoose2 profile image
anonymoose2

We could have what Australia has. But we in the US are way more into war works programs. The “Majority” politicians and citizens really like leaders who like the saying freedom isn’t free. So with that mindset we are stuck with high costs for medical care. Cheers 🍻 Bud Zero 🙂

john4803 profile image
john4803 in reply to anonymoose2

Hey my neighbor works for Boeing and does well and helps the county pay it's taxes!👍

anonymoose2 profile image
anonymoose2 in reply to john4803

Worked for a major Casino corporation in Las Vegas and we had a few that visited the properties that worked at Boeing, and Lockheed and they helped with the tax base in Nevada also. That trickle down economy does work. The problem is government always spends more than they take in and this country as do many have great debt that can’t and never will be paid because of just the math. Yes we could have what Australia has but it would be more debt that can’t ever be paid on our current tax base. It’s our thirst for policies that live off the giant credit card in the sky. It’s based on Keynesian economics. Now don’t get me started! 😆 Cheers 🍻 Bud Zero.

john4803 profile image
john4803 in reply to anonymoose2

I live just West of St. Louis, in a small town, and another neighbor works for McDonald Douglas. St. Louis has them all, including Ratheyon, I think? It's worth it to them to drive quite a ways to work.

Magnus1964 profile image
Magnus1964

The US government is nothing but a piggy bank for big pharma.

de-luke profile image
de-luke

Us Americans need to vote for people who will bring single payer healthcare. The Pharma companies want to stay on their Corporate Welfare supported by American Taxpayers and sick people. GO out and talk about this on social media and write your representatives. Don't let anyone silence you by saying this is "political". Everything is political, including your health.

dhccpa profile image
dhccpa in reply to de-luke

We've always had trouble distinguishing large anti-competitive big business (and anti-competitive professions as well, btw) from the corner convenience store with hundreds of competitors.

shuckymesh62 profile image
shuckymesh62 in reply to de-luke

No way.

jackcop profile image
jackcop

de-luke: " Everything is political, including your health." I don't know if everything is "political", but morally, medications to keep us alive certainly could becme political.

de-luke profile image
de-luke in reply to jackcop

Hi jackcop, Well I guess it depends of what your deffinition of "political" is. When health care is in the hands of politicians it is political. By the way are you the same user as one-eyed-jack?

nitefly50 profile image
nitefly50

Xgeva was part of my ADT treatment for about two years. It cost me about (round #'s) $500/mo. (20%). Insurance covered about $2000/mo. (80%). ADT is categorized as "Therapy". Like Radiation Therapy, which also cost me 20% at the time. My insurance company (BCBS) appears to negotiate prices with providers of services and pharmaceuticals per the summary statements I see regularly. It's a State by State thing in the U.S., I believe.

john4803 profile image
john4803 in reply to nitefly50

I am paying $555/month but I don't understand how I could buy it for cash at $3200 at Walgreens, when it starts out at 10K?

nitefly50 profile image
nitefly50 in reply to john4803

I looked at the Formulary for 2022. Xgeva is listed as a Tier 5 drug. Where I live it is not available in local pharmacies. It is only available from a national distribution company. I received a monthly subcutaneous injection at my urologist's office, as I said, for two years before it was deleted from my treatment. (Eligard twice per year; also subcutaneous. That treatment continues.)

john4803 profile image
john4803 in reply to nitefly50

Yeah, we thought it was a Tier 5, which explains part of the expense. Thanks!

Muffin2019 profile image
Muffin2019

Greed

carbide profile image
carbide

When Profit Is a dirty word.Big Pharma is the problem along with insurance. Fixed system.

GoBucks profile image
GoBucks

My medicare pays for 6 month injection in my Dr office. I pay nothing. I skipped my last shot because my dexascan was greatly improved. ( worked out more & lifted weights)

john4803 profile image
john4803 in reply to GoBucks

I think you are getting Prolia because Xgeva is a monthly injection?

GoBucks profile image
GoBucks in reply to john4803

Nope. Medicare paid for Xgeva which is for metastatic patients. Prolia is for osteoporosis non metastatic.

GoBucks profile image
GoBucks in reply to GoBucks

Of course my Dr may have screwed up. Anyway I am better.

john4803 profile image
john4803

Can't get your link to work?

j-o-h-n profile image
j-o-h-n

CAPITALISM....

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 07/13/2022 6:19 PM DST

john4803 profile image
john4803

It works now. So, in 2020 it was $2352 and the price I got from Walgreens of $3,200 sounds about right, today. So, there seems to be quite a "markup", even though it is a Tier 5 drug. Thanks!

onajourney profile image
onajourney

I had my monthly injection two days ago. The oncology office charged $4,200 for the injection of denosumab, 1mg. My Medicare Advantage insurance paid $2,545.20. The oncology office also charged $50 to do the injection and insurance paid $13.43. I owe nothing.

john4803 profile image
john4803 in reply to onajourney

Sounds great but those charges are a lot less than my insurance co. is being charged?

KocoPr profile image
KocoPr

You should try your hospitals pharmacy.I just got a call today from MGH pharmacy and they found a grant for me that will cost me $0 for Nubeqa. As much as i hate big money in politics there are some grants out there and some very caring institutions.

john4803 profile image
john4803 in reply to KocoPr

I got a little bit of grant money for my Erleada but my investment income (if it lasts under this administration) was too great last year for any more?

KocoPr profile image
KocoPr in reply to john4803

Yes it’s sad you work your whole life saving for retirement and then you get dx, then you start drawing on your retirement and now your drugs eat it all up. I always questioned taking a decent percentage of my payday to sock it away for when i retire and not having that extra money for present day expenses, vacations, toys etc

john4803 profile image
john4803 in reply to KocoPr

The key to investing the stock market is buy stocks of good companies and hold and don't sell in the downturns, because they will come back unless they their doors. Vanguard is the best because they started ETF's which are a combination of many companies to fall back on as the stock market goes up and down.

KocoPr profile image
KocoPr in reply to john4803

I don’t need to worry about that anymore, im retired and drawing on my retirement

john4803 profile image
john4803 in reply to KocoPr

I do both!

Gl448 profile image
Gl448

Thanks for that link, saves me the Google search! MO plans to put me on xgeva next month after my ct guided deep bone biopsy (right acetabulum).

I’ve been signing up for all these copay assistance programs for every drug that’s been in the discussion for me.

Not complaining that these exist, but it just proves in my mind that the drug companies want to milk every penny out of insurance without losing patients (customers) due to high copays.

john4803 profile image
john4803

We want free enterprise (at least I do) & drug companies experience a lot of R&D costs for drugs they develop. But I don't know if that is in play here or not? If it becomes "generic", maybe that will help?

My PSA dropped to 0.1, over the past 5 months, from 7.3 & if it stays at this level, I may go to every 3 month injections? So, that will help, also. But I can't get a straight answer on why it is so expensive.

At my last injection the nurse asked me to warm the drug bottle with my hands, because hers were cold, & I was shocked as to how small it was. It is definitely worth it's weight in gold!

john4803 profile image
john4803

Thanks for the info!

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