Choline and APC.

Choline intake and risk of lethal prostate cancer: incidence and survival - PubMed

pubmed.ncbi.nlm.nih.gov/229...

16 Foods That Are High in Choline

healthline.com/nutrition/fo...

[cesces]

So what doesn't have choline?

[Hidden in reply to cesces]

Water...

I don't go out of my way to reduce choline. I don't think that the cancer link has been proven reliably but it seems prudent to reduce high choline foods unless they might be beneficial.

So for example, I don't eat egg yolks. That is one of my only anti-choline choices. Note that egg whites have very little choline. I down plenty of egg whites.

Some high choline foods are also nutritious and might have some anti-cancer actions. For example, broccoli.

[pjoshea13 in reply to Hidden]

Dangerous to flirt with choline deficiency:

ncbi.nlm.nih.gov/pmc/articl...

-Patrick

[Hidden in reply to pjoshea13]

Moderation seems to be more important than trying to completely abolish a nutrient. That is one of my issues with Keto and Vegan diets. You could supplement up the ying-yang but you rely on our present knowledge of nutrient requirements, not to mention the toxins and heavy metals found regularly by 3rd party labs.I'm also dubious about trying to block every pathway to starve cancer. I've seen some of the restrictions - block some essential amino acids that are required by your brain. Really??? So, either we have brain dead people writing some of these books or they just aren't successfully blocking all the things that they say they do (actually, the brain-dead theory explains a lot )

In the choline case, I think I get adequate choline from broccoli, beans, nuts, and fish.

[Graham49 in reply to pjoshea13]

It's essential for fetal growth, but isn't a fast growing fetus a bit like a fast growing cancer. I seem to remember you previously stating something like this: for an aggressive cancer, survival might be prolonged by an an almost malnutrition diet.

[pjoshea13 in reply to Graham49]

Graham,

I have read that most Americans fall into a narrow range close to minimum requirement. If you cut back too much you may mess up your liver. We put a heavy burden on that organ as it is, so I would suggest that choline is not a candidate for cutting back on.

-Patrick

[pjoshea13]

Oh no! Not Erin the vegan egg lady again. She used epidemiological data to show that half of one egg weekly was dangerous,. Something like that.

Two from the vaults:

healthunlocked.com/advanced...

healthunlocked.com/advanced...

-Patrick

[Hidden]

Egg lady! Lol!

I read some other studies. Some show association and some do not. I don't find it hard to steer clear of egg yolks (and I don't think I need the extra cholesterol or fats). I like egg whites more than yolks (goes back to my more athletic days when I ate rice, beans, egg whites, nonfat milk, and skinless chicken - bleh, maybe my body rebelled and gave me prostate cancer 30 years later).

ncbi.nlm.nih.gov/pmc/articl...

[Schwah]

If I read the study correctly it said that choline intake after being diagnosed with PC had no impact. Correct?

Schwah

[Hidden in reply to Schwah]

Yes. In the top study, the result is trending towards significance. "HR for quintile 5 compared with quintile 1: 1.69; 95% CI: 0.93, 3.09; P-trend = 0.20"

In the lower study, they use asterisks to rank the strength of evidence. The referenced studies varied in risk.

I don't think the data is very robust. So I wiped out egg yolks a few years ago and not much else.

[Teufelshunde in reply to Hidden]

Thanks for your analysis. I hate when i see a broad statement like "eggs are bad". Tell me why? And like you stated, and I read in Dr Greger's chapter on PC, it is choline. No choline, no issue. Like the video recently on how sugar is not an issue as PET scans that rely on sugar uptake dont work on PC (but work on other cancers), PET scans with choline was used so to me this is confirmation of the specific. I have never seen a study that looked at egg whites. Would love to have confirmation of the logic.

[TottenhamMan]

It looks like everything that we can eat is unhealthy for us, including almonds and broccoli.

Does DUST have choline in it? I'm just eating dust from now on.

[Hidden in reply to TottenhamMan]

Dust is good. Just don't put any spice on it.

I'm taking these studies with a big grain of salt. Salmon is arguably very good for us. So is broccoli. Nuts might be neutral but they are a good source of healthy fats and proteins.

The only choline I banned is egg yolks. I posted mostly to get other people's takes on this field.

[TnRebel62]

An interesting read but I think I will keep eating eggs.