In the last 4 years, since failing Enzalutamide I’ve been successfully zapping Mets. In all cases, after radiation my PSA drops from about 20 to 3 slowly over a six month period. PET scans show only 2 Mets at a time. I’ve now had 6 treatments over the past 4 years, EBRT 60gy 30 days. Except for a lymph node all Mets have been on my right pelvis. It’s taken it’s toll, I’m limping and can walk for only 20 mins. My MO (like TA) reckons radiation is for pain relief. My RO reckons, in my case, the treatment works.
After my last zapping in Aug my PSA got down to 6.8 three months ago, but has now jumped to 15. If the Mets are anywhere near any previous zapping I can’t have radiation, in fact, if it’s the right pelvis I won’t. I’m 70 should I be opting for Chemo, “sooner rather than later”. Or, if it’s one or two mets and not on my right Pelvis zap em again. Any advice.
Written by
Ausi
To view profiles and participate in discussions please or .
There is no proof that playing whack-a-mole accomplishes anything. If you continue with systemic therapy and the zapping is in safe places, why not? You are making the common mistake of thinking your PSA is your cancer. It is not. It is just a protein that larger tumors emit- so when you zap the ones you can see, that leaves probably thousands of micromets that you can't see. You have let those micromets establish themselves and grow just because your PSA was low. Systemic therapy is what you need.
We put off chemo for too long and regret not getting it sooner. Most of Grumpy's doctor's were against chemo but now he may need it to qualify for Lutetium.
Be careful as we were told that Radium 223 may disqualify you from other trials.
I am impressed by most people's results from Taxotere. There is such a variation of results and tolerance though! If you research here and on youtube you will learn what to ask for from your MO--to give it a try and see how you tolerate it. Perhaps a reduced dose but I did not read your background for comorbitites. Icing of hands and feet has helped most people avoid neuropathy. And, chemo may reset the cancer so that you can get more time from abiraterone or enzalutamide.
Exactly. I woul do chemo maybe only 4 to 6 cycles if there are side effects and try again with enzalutemide, maybe it works. Radiation only if absolutely nessesery to manage pain.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Chemo/Pluvicto or Clinical Trial?
PSA post salvage radiation
Surgery or radiation, looking for some advices 
Please boys, girls, can anybody advise or help explain why combined carboplatin & etoposide chemo are going to be used in next treatment
Off clinical trial, on to radiation and chemo
