18F-Fluciclovine ( Axumin ) Versus 68Ga-PSMA-11 Imaging for Prostate Cancer Biochemical Recurrence

[maley2711]

cancernetwork.com/between-t...

A nice study, but with important limitations, as discussed by the 2 Docs.

[robertferre]

Last September I had a PSMA scan using Pylarify (see pylarify.com). My opinion is that Axumin used to be the best, but has been surpassed. 68Ga-PSMA-11 is such a short-lived isotope that you need to have your own cyclotron to produce it. Hence, it has been approved at the University of California in LA and San Francisco, as they can make their own. Pylarify is durable enough to be made in one location and expressed to a clinic. My scan was postponed by two days because the morning's production had not passed some quality control test and was destroyed. The second time everything went well. My bone scan had been negative and my MRI inconclusive. But the PSMA lit up like a Christmas tree and showed two small spots of prostate cancer in my abdomen lymph nodes, just above the area previously treated with proton therapy five years ago. Being a new area, I was treated again with proton therapy. Without the PSMA scan, they had all kinds of bad ideas from Hormones to cryoablation of the prostate. The PSMA changed all that and saved the bacon, as it were.