Hey guys P cancer 2. 5 years ago, removed prostate
bad margins post surgery, started lupron 2 years ago along with radiation.
(Triple Play) #9 Rad. treatments went well ,responded nicely to lupron
Dropped PSA immediately , undetectable last 1.75 years
Should I continue Lupron ?? .. Thoughts ?
If no cancerous lymph nodes or distant metastases, ADT for anything over 18 months is probably all you need.
Thanks for the reply TA. by the way I'm 58 years oldSo you think I should continue Lupron?
I have been at <.01 for most of the last 2 years.
Dr. says he would suggest giving it a break and see what happens.
Thinking my 39 radiation treatments and lupron may have done the job.
medicalxpress.com/news/2022...
New study says its more like 26-27 months.
The OP isn't high risk having primary RT, he is recurrent and just had salvage RT.
We don't know what his Gleason score is and he is recurrent after RP. Wouldn't that make him high risk? If he is recurrent doesn't that mean he has metastases (although not visible on conventional imaging). I don't know. Maybe the study I cited does not directly address his situation. Thanks.
"High risk" means localized before any therapy. Kishan used the NCCN definition.
Hopefully, he only has some cancer that has grown into the prostate bed, not metastases.
It's an important study - in fact, I'm writing an article about it.
Diagnosed fall 2019 PSA of 12.....Prostate removal Dec. 2019
PSA 2.5 Post sugery , Started lupron 3 weeks after surgery
PSA dropped to.17
My Gleason score was 4+3 (7)
Cancer was in prostate bed..post surgery...... 39 radiation treatments
After 24 months of Lupron and 18 months undetectable PSA <.01
I am thinking of getting off Lupron Thoughts ??
Diagnosed fall 2019 PSA of 12.....Prostate removal Dec. 2019
PSA 2.5 Post sugery , Started lupron 3 weeks after surgery
PSA dropped to.17
My Gleason score was 4+3 (7)
Cancer was in prostate bed..post surgery...... 39 radiation treatments
After 24 months of Lupron and 18 months undetectable PSA <.01
I am thinking of getting off Lupron Thoughts ??
Last edited by Alex52
Diagnosed fall 2019 PSA of 12.....Prostate removal Dec. 2019
PSA 2.5 Post sugery , Started lupron 3 weeks after surgery
PSA dropped to.17
My Gleason score was 4+3 (7)
Cancer was in prostate bed..post surgery...... 39 radiation treatments
After 24 months of Lupron and 18 months undetectable PSA <.01
I am thinking of getting off Lupron Thoughts ?
The post-prostatectomy psa might have been due to residual prostate tissue left after surgery and not due to cancer. But, since they didn't know they treated you as if you were high risk. I think you are a safe bet to go off ADT since the NCCN guidelines say 24 months.
At 3 months, it is never due to residual prostate tissue. I assume he maent 3 months and not 3 weeks.
Thanks for the clarification. He could have been a little clearer on the timeline. Nevertheless, why can't remaining prostate tissue contribute to the presence of post-prostatectomy psa? Why would it stop at 3 months? I found it interesting to say the least, that Dr. Kwon discussed treating a man after a prostatectomy who was found to still have his prostate.
Yes. That is long enough even if pelvic lymph nodes were detected.
What was your Gleason score? This could affect what you're comfortable doing with ADT.
Greetings Alex52,
Please tell us your bio. Age? Location? When diagnosed? Treatment(s)? Treatment center(s)? Scores Psa/Gleason? Medications? Doctor's name(s)?
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THANK YOU AND KEEP POSTING!!!
Good Luck, Good Health and Good Humor.
j-o-h-n Thursday 01/20/2022 10:38 PM EST
Still waiting on yours. Practice what you preach Mr. Not funny.
To Nameless999,
See my private post to you....
Good Luck, Good Health and Good Humor.
j-o-h-n Thursday 01/20/2022 11:19 PM EST
Your private post to me 01/21/2022:
Nameless999
As soon as I see your medical history . I'm going to start grading your incredibly poor attempts at humor. 0 the lowest, 10 the highest. Good luck. As far as private posts to me... I have you muted.Don't drink to much today.
4 hours agoReportMute
My private post response to you 01/21/2022:
Me
No problem.......
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 01/21/2022 1:20 PM EST
a few seconds ago
There are few class acts like you left in this world John. You are a true gentleman.
Thank you sir...... sometimes my silly humor gets me in trouble..... (but I believe it helps)... When I was getting fried by Dr. Zeleksy in MSKcc I was fooling around and laughing with the technicians. Another paYtient also getting radiated approached me and said "You're the happiest guy I ever saw who's got cancer"..... my response was "I rather laugh than cry".......
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 01/21/2022 2:01 PM EST
Been telling my kids " I have a choice, laugh or cry, and crying never help with anything." Life Is Good. especially with a good belly laugh--like todays news--Pos covid test this morning.. WEE---
Just for you and not the kids.
So this woman is sitting next to this guy on an airplane. She is constantly sneezing and then sighing and breathing heavily for a few minutes.The guy is concerned and asks the woman "if she needs help?"
The woman shyly whispers to the guy "that whenever she sneezes she has an orgasm".
The guy says "oh my, are you taking anything for it?
The woman replies "yes, black pepper".....
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 01/21/2022 5:55 PM EST
There's life after Lupron!
Last lupron
Lupron side effects 
Lupron ONLY or Lupron AND Cassodex?? 
Started on Lupron and later Casadex off and on + Lupron
