Significance of FANCA in Genetic Testing - Advanced Prostate...

Advanced Prostate Cancer

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Significance of FANCA in Genetic Testing

DJBUNK profile image
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I just received the results of a genetic test ordered by my oncologist. It shows that I have a genetic variant in the FANCA gene. I have an appointment with my oncologist in a few weeks and he is going to to set up a meeting with a genetic counselor to go over the results.

From what I can tell, the significance of this variant is a predisposition to PCa, which... as a G9 patient who has already had surgery, radiation, and ADT...may explain why I developed cancer but I'm wondering if it has any significance on future treatment decisions. I suspect this information is important for my son's to know.

I have no doubt that my doctor will explain the test results but I want to go into the appointment with a better understanding so I know what questions to ask. Does anyone have any insights to help me be better informed?

Thanks in advance

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DJBUNK

Thank you for the reply Nalakrats. One additional factor that I noticed after I posted is that the report states the variant is pathogenic. As a medical neophyte, I had to Google pathogenic. It appears to me that my report is indicating that the FANCA variant was due to exposure or some other external influence. Is that a correct interpretation?

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