An appropriately named gene could be a new treatment target

[SimonHL]

An Unexpected, & Novel, Target for Prostate Cancer – Our Biological Clock

news-medical.net/news/20210...

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

nature.com/articles/s41467-...

[TheTopBanana]

Thank you for posting this. Its so interesting if this means treatment should be given a specific time of the day. I understod that CRY-1 should be targeted and inhibited? I wonder what that does to the sleep cycles?

[Spyder54]

Thanks Simon,I agree. I am certain that healthy sleep patterns are one more important pieces of the puzzle (as I type here on my bedside iPad at 5:30am-at least went to sleep at 10pm).

We want DNA Damage to PCa cells, not DNA Repair of PCa cells. I have the ATM gene which also negatively repairs the DNA of PCa cells.

This Cry-1 is one more overlooked piece of the puzzle which will lead us to better outcomes. Will focus on healthy bedtime rituals/habits!

Mike

[TheTopBanana in reply to Spyder54]

Do you understand the meaning of targeting CRY-1? What would that do to ones cycles?