Glutaminase inhibitor trial

[hg115pb]

There were some posts recently re the possible role of the glutaminase switch in leading to castration resistance. The following trial - A Phase II Study of the Glutaminase Inhibitor Telaglenastat (CB-839) in Combination With the PARP Inhibitor Talazoparib in Participants With Metastatic Castration-Resistant Prostate Cancer is opening in July to test this option

Although it includes a PARP inhibitor, this trial is looking at only men who test negative for BRCA.

clinicaltrials.gov/ct2/show...

[CSHobie]

Very interesting post and thank you Nal for the reply. Glutamine seems to be an important factor in CRPC disease. I might be looking on Amazon for Ashwagandha, LOL

[TFBUNDY]

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