Valaciclovir: I saw this on another... - Advanced Prostate...

Advanced Prostate Cancer

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Valaciclovir

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I saw this on another site:

There is an interesting article showing that when men who have prostate cancer develop shingles and are given valaciclovir, there seems to be significant prostate cancer cell death.

europeanurology.com/article...

This study only involved two men, but the results were impressive. It would be interesting to see if these results hold up in a bigger study."

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pjoshea13 profile image
pjoshea13

Shingles is an oportunistic condition that surfaces when immune function is compromised. Shingles vaccines are only partially effective.

When my wife had a recurrence of a plasmacytoma in 2015, she developed shingles. She received Aciclovir for 4 days, but was in hospital this time 5 years ago, for pain management.

Her oncologist told me that more than half of his multiple myeloma patients develop shingles. His approach was to use Aciclovir continuously. Her current oncologist has had her on 500mg Valaciclovir prophylactically for over 3 years. Note: Valaciclovir is a prodrug for Aciclovir.

One of the study cases cited "was treated with valaciclovir 1 g tid over 10 d". This is somewhat in line with conventional short-term treatment that her doctor prescribed. However, note that Valaciclovir can also be used continuously.

"Aciclo-GTP, the active triphosphate metabolite of aciclovir, is a very potent inhibitor of viral DNA replication."

en.wikipedia.org/wiki/Valac...

-Patrick

TheTopBanana profile image
TheTopBanana

Thank you for sharing! May I ask which other site? Merry christmas!

in reply to TheTopBanana

Sure!

Facebook: Prostate Cancer - Latest Research and Treatments

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