PSA J U M P to 0.800 Time to PANIC! Or not?

[depotdoug]

Had my 12/15 PSA done yesterday and up to 0.800ng/mL from NOV 17th of 0.536ng/mL

>>> Two different factors involved in these reads:

1. Blood draw @ my PCP DR office Ft Wayne,IN.

2. Found they send Blood vial to IU Health Ball Memorial Hospital Lab Muncie IN. Different lab and 60 min IU Health courier transport....

PSA 0.800 ng/mL Date: Dec 15, 2020 11:20 a.m.

PSA 0.536 ng/mL Date: Nov 17, 2020 09:21 a.m. PSA 0.485 ng/mL Date: Sep 18, 2020 10:10 a.m. PSA 0.754 ng/mL Date: Jun 08, 2020 07:31 a.m. PSA 1.032 ng/mL Date: Mar 10, 2020. 12:00 pm.

Concerting concerned rise???

Thoughts?

Depotdoug

[GP24]

You have to continue on with Abiraterone/Lupron/prednisone treatment anyway. Panic will not help.

[depotdoug in reply to GP24]

No panic yet or this Friday either.

I see my med onc this Fri 11:40.

Disconcerting is my “BNP” cardiac protein marker heart function lab test.

BNP PI QN read of 404. Limits are 0-100 pg/mL Time to call cardiologist at 08:00

[GP24 in reply to depotdoug]

I think you onc will say, the rise is not that significant yet to change to different drugs. I would wait until the PSA value gets above 2.0 ng/ml. You could try to increase the dose of Abiraterone now. I cannot comment on the BNP marker.

[depotdoug in reply to GP24]

Good news my CT abs/pelvis/chest and NM bone scan 11/17 showed no, absolutely none detected signs of cancer at those locations. No bone metasisis(sp).

I will call my cardio RN at 08:05 and leave a message. Hard to shake an answer from my Cardio team. They busy. Guess i’ll leave an urgent message. Re: BNP( oh that cardiac blood protein marker) also relates to my leg swelling from 4 days inpatient 12/4-7, acute diverticulitus. Flatbon my back w/ 2 IV’s antibiotics.

Phone calls in 90m.

Thxs. GP24

[Tall_Allen]

PSA is still low.

[depotdoug in reply to Tall_Allen]

Thxs, I was so wanting an = to or lower PSA, then my BNP cardiac protein marker blood level of 404 pg/mL hit me from the same list of labs i got over whelmed.Well my Cardiologist visit last Friday told me my Leg swelling Edema probably caused by Prednisone. I tend to agree.

Plus i was inpatient in hospital Dec 4-7 with

Acute Diverticulitis. 4 days IV’s , Zoysn( piperacillion) , morphine, and potassium.

My BNP lab numbers (high) got me too over cautious with every lab test i had Tue.

Great to be Diverticulitis out of Hospital jail since 12-5.

Doug

[CalBear74 in reply to depotdoug]

Doug, are you taking BP medication? I’m particularly interested ifyou are taking possibly a calcium channel blocker (especially amylodipine) for blood pressure. I had Edema also. Apparently amylodipine caused Edema in 4 other case studies of BP management. A friend, who is a retired pharmacist, warned me that edema is consistent with calcium channel blockers and the way they work to reduce blood pressure.

[depotdoug in reply to CalBear74]

Yes sir, Amlodipine 5mg once a day.

Ooops i think my, i’m sure my newest Cardio Doc said Amlodipine can cause edema.. yes he did. He also stated that my Prednisone 5mg twice daily could cause leg feet swelling.

I be waiting for a rtn call from my Cardio RN still today...

Thxs for info and path forward.

[TEBozo in reply to CalBear74]

Amlodipine made my ankles swell.

[depotdoug in reply to CalBear74]

Yes sir. Amlodipine 5mg per day along with three other BP meds.Way too many. Here they are.

1 CARVEDILOL 25 mg 1 Tab AM 1 Tab PM Hypertension

2 LOSARTAN 50 mg 1 tab AM 1 tab PM Hypertension

3 AMOLDIPINE 5 mg 1 tab AM only Hypertension

4 Buspirone 7.5mg (3X/day) AM Lunch PM Anxiety

5 Abiraterone Acetate 250mg 1 TAB w/Low Fat Bkfst Cancer med

6 Lupron Depot 90 Days Injection ADT Cancer

7 Prednisone 5mg once daily Reduce Mineralocorticoid

8 XARELTO 20mg w/dinner Blood Thinner

9 Furosemide (Lasix) 20 Mg 1 tab AM H2O retention

10 Potassium CL ER 10 MEQ

_________________________________________________________________________

I agree with Amlodipine as a edema swelling drug. I've experienced that way to many times.

Thanks for the input CalBeaer74.

Doug

[tango65]

The PSA is still low, you need to repeat the study , probably monthly if possible and determine if there is a consistent upward trend.