There is a cross-resistance between Abiraterone and Enzalutamide. Therefore Enzalutamide will not work or just a few months after Abiraterone. Many doctors recommend Enzalutamide after Abiraterone just to see if it works for a few months.
A chemo with Docetaxel is the usual treatment now.
Pain is often caused by metastases in the bone. He can have these radiated to reduce the pain.
Chemo is no longer the "last option" that it was; in fact, evidence points to success with using Chemo as a first line or one of the first lines of attack. Wishing you the best.
There are different drugs for chemo therapy for the different kinds of cancer. What you heard may not apply to prostate cancer. For prostate cancer you use Docetaxel which does not have the same side effects other chemo drugs do. However, it does have side effects.
What you can do is select a two-weeks schedule with a lower dose. This reduces the side effects.
If you just address the pain with radiation and drugs it will get so bad that you cannot control the pain any more.
Try it. He can always choose to stop. Most find the docetaxel side effects fairly mild and tolerable. Ice for hands and feet help protect them during infusion.
Ah, no wonder then that the idea of chemo would be terrifying. And some forms of chemo for some cancers are indeed very intense and difficult. But the taxols for PC are generally not so bad at all for most of us. I lost my hair and had fatigue which resolved in time. Now it is 13 years later and I'm rolling along. Docetaxel might also restore responsiveness to enzalutamide and AA to get still more good mileage from those. Sorry for the loss of your friend's mother. But her case was undoubtedly different altogether.
He has to try it and see if he can tolerate it, for my father Docetaxel was pretty bad but not unbearable, at the end it still increased his lifespan by over 6 months, and he had side effects only for one month, so was worth it ultimately.
Chemo is very individual, for some people it's highly toxic, while for some others it causes almost no side effects.
The Oncologist will adjust the chemo dose if needed. My husband always had a low dose of Docetaxel because he had a bad reaction, and his PSA reduced by half after each infusion. It’s worth to try it. Of all the treatments he had, Docetaxel was the most effective.
Hello Vasanta, I can not give you medical advice but I will tell you that in all the years I have been on this forum I have not seen or heard of any member who ever passed away due to Chemo. Like the advice you received from other members you can always stop the treatment. You are the caregiver. Peace and Prayers be with your Father.
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