Omega 3, PCa, Cardiac

If high omega 3 status is linked to cardiac disease benefits and no changes to PCa then it seems prudent to make sure to get some each week.

sciencedaily.com/releases/2...

[Hidden]

I try to make sure I get some omega-3's at least twice a day (fish oil and olive oil). But I might only have salmon a couple times a week.

[wilcoxsaw]

My GU oncologist, nationally known lecturer and director of the GU oncology dept at a internationally known comprehensive cancer center, recommended I not continue omega 3 given research that doc has reviewed.

[Hidden in reply to wilcoxsaw]

Perhaps from these studies: mayoclinicproceedings.org/a...

Most of the negative evidence seems to not so much stem from supplements or fish consumption, but rather from a correlation between high plasma levels to PCa. Could be high estrogens that are the actual cause and O3 status in blood is just a coincident marker. I do not know but just am throwing that out there.

From this mayo article:

"In men who already have prostate cancer, a

regular high intake of fish has been linked to a

marked increase in survival. An analysis

derived from the Physicians’ Health Study

found that prostate cancer patients who ate

fish at least 5 times weekly had a 48% lower

risk of death from this disease than those who

ate less than one fish meal weekly.15 In a Swedish cohort, patients with prostate cancer in the

fourth quartile of total marine omega-3 consumption were 40% less likely to die of prostate

cancer during follow-up than those in the first

quartile.16 In an in vitro model of hormone

ablation and evolution of androgen independencedin which androgen-sensitive prostate

cancer cells grown in charcoal-stripped serum

grow slowly but gradually achieve a marked increase in growth rate over 10 weeks of incubationdconcurrent exposure to EPA or DHA

prevented this increase in growth rate, suggesting that fish oil might slow the transition to

androgen independence in patients with prostate cancer.17,18 Diets enriched in fish oil, or

in the terrestrial omega-3 stearidonic acid

(18:4-n3; readily converted to EPA in the

body), have slowed the growth of human prostate cancers in nude mice.19-22"

[Hidden in reply to Hidden]

Very recently I researched the subject for the reasons I lay-out in this post:

healthunlocked.com/prostate...

The whole story started in 2013 as a secondary-conclusion of the SELECT trial.

During the years that followed there were papers that questioned the validity of it.

(This is the nice thing with medical studies. To each one saying North there will be another saying South). The latest one of July 2019 says differently:

"We found that high LCω3-eicosapentaenoic acid (EPA) level in prostate tissue (odds ratio (OR) 0.25; 95% (confidence interval (CI) 0.08–0.79; p-trend = 0.03) was associated with lower odds of high-grade PCa. Similar results were observed for LCω3 dietary intake (OR 0.30; 95% CI 0.11-0.83; p-trend = 0.02) but no association for RBC. LCω3-EPA levels in the target prostate tissue are inversely associated with high-grade PCa in men with low-risk PCa, supporting that prostate tissue FA, but not RBC FA, is a reliable biomarker of PCa risk."

ncbi.nlm.nih.gov/pmc/articl...

What I understood from my reading (I may have got it wrong) is that under the Ω acid (3-6-9) label a number of them are housed. Eicosapentaenoic acid EPA and Docosahexaenoic acid DHA originating from fish oil are ok. Supplements combining the former with others of vegetable origin, like flaxseed oil, may not be. Virgin olive oil the basis of the Mediterranean diet is ok.

[j-o-h-n in reply to Hidden]

For me anything virgin is okay....

Caviar comes from virgin sturgeon;

Virgin sturgeon's a very fine fish.

Virgin sturgeon needs no urgin';

That's why caviar is my dish.

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 06/07/2020 8:01 PM DST

[SPEEDYX in reply to j-o-h-n]

That bares closer eggsamination!!!

[j-o-h-n in reply to SPEEDYX]

Caviar in a jar by far........ (roe roe roe your lifeboats)....

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 06/07/2020 11:26 PM DST