Cervical lesion

[dpowellnt]

After almost five years of slowly increasing PSAs (and failed oral chemo drugs), I finally got my first detectable lesion.

It is on the posterior aspect of the 6th vertebrae.

My question is what can I expect now (currently starting Docetaxol, had one appt of 10)? Will they use radiation or surgery? Since I'm on chemo already will they wait? How serious is it since it is in a cervical vertebrae.

[Tall_Allen]

There are no oral chemo drugs for prostate cancer. You can expect docetaxel will shrink your metastases. If it is large they can zap it with radiation in a single dose to prevent spinal compression and pain. If it's small, you may not need that. Discuss with your doctor whether a bone preserving agent makes sense for you. Ask for a DEXA scan. Also, good idea to get Neulasta with your chemo to preserve immune function in these dangerous times.

[dpowellnt in reply to Tall_Allen]

Sorry. Meant, Xtandi, Erleada, Zytiga with Predizone, Casodex, and of course Zolodex and Lupron injections.

All failed.

Thanks for the advice. I will talk with my doctor on that.

[Schwah in reply to dpowellnt]

And theres the potential added benefit of zapping the met. Many drs believe and some preliminary studies seem to hold out hope that radiating individual mets, for ogliomastatic men (5 mets or less) may extend your life.

Schwah

[Gearhead]

Because I don't see many posts involving cervical spine mets, I'll summarize my situation, which may or may not have any relevance to your situation. "C6-C7 osseous metastatic disease with extraosseous extension into the left paraspinal and epidural space" was detected by an MRI in late 2018 before I had any idea that I had PCa. The usual diagnostics confirmed that I have PCa and this spine met (some details are in my profile). Have been on Lupron + Zytiga + Prendisone + Xgeva since February 3019. PSA quickly decreased from 111 to < 0.1. October 2019 MRI indicated no growth of met. My oncologist's strategy is to continue this regime until PSA increases. I have nothing more that all the usual ADT SEs, and no bone pain, so this strategy seems prudent to me.