18F-DCFPyL PSMA PET/CT for Lu-177 eligibility evaluation

[Shanti1]

The 18F-DCFPyL PSMA scan is potentially superior to the Ga68-PSMA scan and we have been accepted into a trial using this scan at no cost.

My question is, is the 18F-DCFPyL PSMA scan readily accepted in Germany as proof of PSMA avidity for potential LU-177 treatment or is it better to get a Ga68 PSMA since that is what the doctors are used to evaluating?

I can't say how much this site has helped us, I am so grateful to all of you who share, learn, and are of service here.

[GP24]

It makes no difference. Both scans are readily accepted in Germany as proof of PSMA avidity. Some clinics use 18F-DCFPyL, some Ga68, some both.

[Shanti1 in reply to GP24]

Thank you, I didn't realize that both were used in Germany. We will probably move forward with the 18F-DCFPyL PSMA.

[jdm3]

Just curious which trial. I did a trial through Johns Hopkins (Dr. Ken Pienta) in 2017 with the 18-FDCFPyL. They were very good.

All the best.

[Shanti1 in reply to jdm3]

I called them about this trial:

clinicaltrials.gov/ct2/show...

but was referred to what I assume is this trial:

clinicaltrials.gov/ct2/show...

It says it is closed, but the recruitment coordinator told me they had reoppened it. We were only offered the 68GA-RM2 through the first trial link above, which is not PSMA bound.

[jdm3 in reply to Shanti1]

👍 Looks very similar. Hope it goes well 🙏

[Shanti1 in reply to jdm3]

Thank you