Has there been a clinical study on Pr... - Advanced Prostate...

Advanced Prostate Cancer

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Has there been a clinical study on Prostatic Artery Embolization and the impact it may or may not have on PCa?

vforvendetta profile image
7 Replies

This procedure has been around for quite some time for BPH, specifically targeting patients that have large prostates or patients that balk at other procedures like TURP, Urolift, etc.

hopkinsmedicine.org/health/...

If cancer requires an active blood supply, would starving the prostate of blood through PAE in theory reduce the chance of PCa developing and/or spreading and/or delay its progression?

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vforvendetta
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Tall_Allen profile image
Tall_Allen

It doesn't seem to be all the effective for BPH, let alone PC. Remember that tumors create their own blood supply.

vforvendetta profile image
vforvendetta in reply to Tall_Allen

Thanks Tall_Allen for the reply. I have BPH - and being mindful of my father's PCa, I am trying to keep the future in perspective.

vforvendetta profile image
vforvendetta

It truly is amazing to think about how much blood passes through the prostate! Thank you for the interesting and insightful response, Nalakrats.

vforvendetta profile image
vforvendetta

I did some additional Googling this morning and I don't know how I missed this yesterday...

ncbi.nlm.nih.gov/pubmed/295...

To make a long story short, it had some impact, but warrants further research.

vforvendetta profile image
vforvendetta in reply to vforvendetta

Reading the above Pubmed article prompted me to Google the different PVA sizes used in PAE. It would be interesting to see what the outcomes would be for PAE on PCa (as a preventative and/or secondary treatment) when 50-μm plus 100-μm PVA particles are used. Maybe a decade from now we will know more.

ncbi.nlm.nih.gov/pubmed/302...

Jbooml profile image
Jbooml

Ctc’s are facilly able to find a nesting site through return veins that includes the gu and vertebral vessels. That’s why so many of us end up with spinal and rib metastases. If the cancer spreads only by this means and not the lymph I believe ablating the prostate to reduce the chances of escaping ctcs bears merit. But Given the microvasculature involved it probably causes more harm than good. I pay very close attention to my urine retention as a measure of what the hornets nest of primary cells are up to and find that the turmeric pepper brew I take daily generally improves my retention....I took a month off and found myself pissing well inside of two hours repeatedly...I’m back on my routine and sleeping through the nights without the early morning relief call. Is the turmeric suppressing cancer cell growth in my prostate...allowing research to find a more enduring therapy than ADT....it’s my hope, but it’s a long shot.

j-o-h-n profile image
j-o-h-n

Difficult to pass through mine... mine is a jar that my urologist uses as a paper weight.

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 12/28/2019 11:56 AM EST

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