Update on my father and questions regarding liver mets.

[BarronS]

Last time I posted, my father had to be rushed to hospital because he was just failing. Tired, couldn't breathe, had to have a cane to walk. In the hospital, his WBC went up to 64 thousand and his blood work was all over the place. He ended up having a small stroke and also went into stage 4 kidney failure. We thought he was going to die.

Fast forward 5 weeks later and he is almost back to normal, which is pretty amazing. Back to working around the house and working at an auction house. WBC is down to about 20k. We thought it was initially acute leukemia, but he wouldn't be alive and doing well right now if it was. There was a spot on his lung but we believe it is an underlying infection that just wont go away, because his WBC is still elevated.

Besides the mass in his lung, a mass that couldn't be ruled out was seen on his liver. It was a small hypodense mass that could be focal fatty infiltrate. This is what I'm very worried about because I see the severity of liver mets.

I was just wondering if anyone has liver mets and how they are doing? What would be the chemo involved if we find on the next PET that there is an increase? What a roller coaster.

[Tall_Allen]

My friend has many liver mets. He was treated with cabazitaxel+carboplatin, which helped for awhile.

[SuppWife]

I’m so glad your dad pulled through that scary situation!

[tallguy2]

Very happy to read this encouraging update!

[Pierreb]

Happy to hear that your dad made such an amazing recovery. That is wonderful news!

[Easey]

I have liver mets , right lobe only as per imaging and I am going in for a procedure called SIRTS tomorrow followed by chemo ( cabazitaxel mid January). The liver mets were first spotted @ August 2017 since then I've had chemo (docetaxel) which worked for a while followed by a trial (immunotherapy plus parp) which worked very well for a while followed SBRT which worked very well for a while followed by another immunotherapy plus ? which didn't work at all. And I'm feelin' good. I sometimes feel a stabbing pain on the right side where the liver is - but that is usually after a big weekend. My wbc is low (neutropenic) following one hit of cabazitaxel a month ago, it didn't help that at the same time I was struggling with a lung infection which ended up being early stage pneumonia . Hoping tomorrow may bring a little more optimism my way in 2020.

The parp inhibitor I was on was rucaparib which which worked really well for about 6 months. The oncologist is leaving out carboplatin for now -

Good Luck

John

[KJMinPhx]

My friend and I met often to share our PCa progress. He had a lot of Mets to the bone, but 6 weeks ago scans showed a met to the liver. He died last Friday.

[monte1111 in reply to KJMinPhx]

Sorry to hear about your friend.

[j-o-h-n in reply to KJMinPhx]

I'm sorry too........... He's in good hands now... Bless him.

j-o-h-n Wednesday 12/18/2019 5:28 PM EST

[vandy69]

I was diagnosed with 20+ liver lesions by a MRI in September 2017. CT guided biopsy confirmed that these were PCa mets. Already had mets in lymph nodes. Had a port implanted in my right chest and began chemo with Docetaxel/Carboplatin combo. Normal round was 6 cycles, 3 weeks apart. Rechallenged with Xtandi after chemo.

Have done this treatment multiple times, for a total of 16 chemo infusions.

During last round, I took Xtandi PLUS chemo. Results were so good that I was able to stop chemo after 4 cycles.

For me, this treatment plan has worked. Lymph nodes have gotten smaller as have liver lesions. PSA currently holding at .2 after a high of 48 eight months ago.

Best Wishes. Never Give In.

Mark, Atlanta

[monte1111 in reply to vandy69]

Wow. 0.2 sounds good. Keep on kicking it!

[j-o-h-n]

Sorry I can't answer your liver question, but I do want to congratulate your Dad on his recovery.

Tell him I'm the guy with paddle number 44....

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 12/18/2019 5:31 PM EST

[Radtech40]

Hopefully it is just a fatty infiltrate and you dont have to worry about that. However, they would most likely treat with chemo, my friends dad that I work with had a few liver mets and they have been stable for about 4 years now. It really is all about how a person responds to treatment, but there are plenty of treatments out there today. Good luck and so glad your dad bounced back. I keep telling my father, its just not your time, each time he hits a bump and bounces back!