‘Trojan horse’ anticancer drug disguises itself as fat. Promising system delivers chemo drug straight into tumors with fewer side effects

[Pierreb]

New drug-delivery system disguises chemotherapy drugs as fat, fooling quick-growing and hungry tumor cells that consume the nutrients much faster than normal cells. The drug then activates, suppressing tumor growth. The drug also is lower in toxicity than current drugs, leading to fewer side effects...

news.northwestern.edu/stori...

pubs.acs.org/doi/10.1021/ja...

[HOPEFULSPOUSE]

So interesting! Thanks for posting. Particularly interesting that he is a chemist rather than a medical oncologist.

[Bjry in reply to HOPEFULSPOUSE]

I hope the fact that the researcher is a chemist and not an oncologist doesn't limit the chances of this treatment option being pursued through clinical trials.

[pjoshea13]

Thanks Pierre,

I wish more members would post the study AND the paper, as you did - including me.

This is particularly interesting, since PCa cells continue to prefer fatty acids - primarily palmitic acid - whereas most cancers favor glucose.

(Some advanced PCa cells do switch to glucose, however.)

-Patrick

[Magnus1964]

Great information, thanks for sharing.

[monte1111]

Knew those Trojan condoms would come back to haunt me.

[monte1111]

Don't guess bone cancer is same as prostate cancer metastatic to bone. But this project sure seems to be close. Whatever happened to the Manhattan Cancer Project? It is just like dangling shining crystals before us, and then snatching them back. If we are going to go bankrupt, and become a third world country, can't we spend some of the money we don't have to control/cure cancer? Our last gift to the world.