Shingles shots and PCa meds?

[JazzMan42]

I'm on Lupron/Zytiga/Prednisone and soon on Xgeva. Has anyone been aware of any interactions between these meds and the new shingles vaccine? I will see my MO later this month but, as we all know, they don't know everything.

[ctarleton]

Since those prostate cancer drugs are working on the systemic Androgen chemical agent axis, or the bone health side of things, .... and are not targeting the immune system, I would think it would be unlikely that there would any significant drug interactions with the new Shingles drug, Shingrix, which works in the virus & immune system realm.

See also:

fda.gov/media/108597/download

(Not a doctor)

Charles

[NPfisherman]

I am on Lupron.... no idea how many IQ points that cost me... 2 ain't bad...

Fish

[6357axbz]

I’m on prednisone, bzytiga and Lupron and my MDA MO said no problem with shingrix. I have had that new vaccine.

[tango65]

When I consulted about vaccines they advised me no to take live virus vaccines. Shingrix is not a live virus vaccine. It contains one protein from the outer shell of the zoster virus.

drugtopics.com/shingles-vac...

[Magnus1964]

Mmmmm, my wife wanted the shingles shot and was told not to get it while I was on xtandi.

[larry_dammit in reply to Magnus1964]

question. Why no on the shingles shot, I’ve been on Xtandi now since 12 of 16. My doctor said get the shot ???

[EchoII]

I am on Luperon and Zytiga, together with prednizone and a bunch of bone meds and blood pressure meds. Had a shingles shot last week with no apparent interaction issues. My mo said there should be no problem and there was none.

[Janis_Kinne]

I’m on xtandi, Degarelix, Crestor, aledronic acic (fonat) and I got shingles 4 months ago. It was awful but it has receded significantly now. No dramas other than intermittent stabs of pain in my back and sides. I imagine no need for a shingles vaccine now especially as for the las two months my PSA is at <0.010

[Kevinski65 in reply to Janis_Kinne]

I woman was cured of advanced breast cancer because she contracted measels. Her immune system got fired up. Did your PSA drop after shingles?

[Janis_Kinne in reply to Kevinski65]

Psa was on a gradual downwards trajectory anyway from xtandi from about 2.0 over 5 months down to .19 but I was surprised that it went to <0.10 for two months now.

[GeorgeGlass in reply to Kevinski65]

I think I'll skip the MMR vaccine after hearing this.

[DenDoc]

I got it. I am post-chemo therapy and currently on Lupron and Xtandi. It is not a live vaccine.

[j-o-h-n]

Had my shot... no problem....

Good Luck, Good Health and Good Humor.

J-o-h-n Saturday 05/04/2019 12:19 PM DST

[JazzMan42]

Thank you all - seems the consensus is no negative interactions with PCa meds.

[monte1111]

Ok. My laugh of the day. Thanks.