HMMM..My hunch has some likely merit

[Jbooml]

I've been looking into AR variances and the metastatic 'drift' in Pc cell metabolism...

Its not lost on researcher's focus as well

eurekalert.org/pub_releases...

This is somewhat disturbing in that targeting the mitochondria isn't something tinkering with can be done without certain risks.

[j-o-h-n]

Tell us about yourself. Thanks.

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 03/21/2019 7:33 PM DST

[Jbooml in reply to j-o-h-n]

Hi John.....nothing much to tell, A guy with an unfortunate diagnosis living as well allowable between medical visits to and from my British Columbian home in the Canadian Rockies and Vancouver....this has limited my other interest in outdoor pursuits lately....the stuff you see in travel journals involving women 30 years junior in tights and Arcteryx puffy coats. I don’t talk about what I do for a living...I don’t define myself this way...by the way I hope to be in India this fall and hope to hook up with whatsinaname....he sounds like my kind of guy. I’m Married to a very loving and concerned woman half my size and have three grown wonderful menchildren. I love golf....my one self allowed vice....golfers aren’t schooled to play 16 hrs straight on a ‘bender’..they’re born that way....it’s just unfortunate, towit, that so few of us are rewarded with a weekly paycheck.

Thanks for asking....I’ll slowly figure all your complimenting and compromising attributions through these conversations...I’m not one to extend to or request of anything others don’t openly share without a stiff prod.

[j-o-h-n in reply to Jbooml]

To Jbooml,

Thank you for your reply. I envy your life style. I was asking more about you age?

prognosis? treatment? treatment center? and doctor(s) name(s)? This information is voluntary and we ask only because it helps us help you and also helps us. Enjoy yourself.

Re: GOLF. When I was younger and not fighting this disease I had lots of ones in holes in lieu of holes in one.👀

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 03/22/2019 12:01 PM DST

[Jbooml in reply to j-o-h-n]

My diagnosis came as surprisingly as dire. I had ignored severe symptoms in light of a miraculous relief of symptoms after a bicycle fall and broken ribs. My 2 year ongoing self diagnosis was an infected hypertrophic prostate as my father had dealt with what i believed a similar Dx...but you dont have your prostate surgically removed with bph...which it turned out he had...but didnt tell us. I was diagnosed last November finally with stage 4 mPC...No biopsy attempted due to the advanced stage..I was mostly metastatic on my right upper femur for the most part and no lymph involvement etc as best they can tell. I get the impression that my medoncs best not investigate the cancer's progress for fear of upsetting it...leaving sleeping dogs lie as it were. I was pursuaded somewhat reluctantly to start bical and eligard which brought my cancer into crashing check...I came to my senses when no one would entertain my lofty wants for enzalutamide and or lutetium theranostic treatment....I was offered aberaterone recently for compassionate reasons and agreed to swap it for bical. My life has resumed normalcy with the cancers retreat. I'm thrilled by yesterdays post regarding the Protac from George71...I hope to pursuade my Docs to let me join the trial....Maybe they'll agree to silence me and my constant upgrade pleadings. I have no dispute with ADT etc except for the fact it offers no likely cure.

[j-o-h-n in reply to Jbooml]

Quite an adventure to say the least. Keep bugging those doctors... As you probably surmised Humor is my Hobby. So here goes one:

A doctor and his wife were having a big argument at breakfast.

"You aren't so good in bed either!" he shouted and stormed off to work.

By mid morning, he decided he'd better make amends and phoned home. After many rings, his wife picked up the phone.

"What took you so long to answer?"

"I was in bed."

"What were you doing in bed this late?"

"Getting a second opinion."

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 03/22/2019 5:54 PM DST