Indomethiacin Question

[BrianF505]

After reading about the studies using indomethiacin with Xtandi as a AKR1C3 inhibitor to maybe stop Xtandi resistance,

I’m interested in knowing from those taking the indomethiacin, what doses are you taking?.

Been on Xtandi for 5 years this month with great success. Albeit the side affect for me is profound fatigue.

Last PSA (this week) was 0.10. Slightly up from September PSA of O.06. As a side note, PSA seems to bump a bit this time of year then drops a bit by summer. Plus it was taken at 10 am, vs normal time of 3-4 pm. It may all be nothing or something. Might just be my slight paranoia. 😳

After all, who wants to see their psa go up?

[NPfisherman]

Message Gusgold ....he takes indo with enzalutamide... got himself to undetectable...

Fish

[tango65]

There is a trial of indo and enza at the University of California Davis:

clinicaltrials.gov/ct2/show...

Here is the dose they use for the trial:

studypages.com/s/a-study-of...

This is a contact number is you need more information from them:

916-734-3771

[Crabcrushe]

Love to be that paranoid; mine doubles like bunnies.

[curious-mind1]

Does anyone know if taking Indomethiacin with Zytiga could also have similar effects?

Arthur

[Rilu in reply to curious-mind1]

Yes, you can take the same results

ncbi.nlm.nih.gov/m/pubmed/2...

What I do not know is whether it is better to take indomethacin when zytiga still works or better when it stops working. Does anyone know?