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Advanced Prostate Cancer
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Statins reduce risk of developing PCa, as well as dying from it

Yet another report on the beneficial use of statins in relation to PCa:

1. health.harvard.edu/blog/lon...

2. ncbi.nlm.nih.gov/pubmed/303...

Arthur

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I've read a few news articles on this report but none of them mention dosage? My dad is only on 40mg of Avorstatin. Anyone know if that would be sufficient and if Avorstatin is a good one to take? Also the second study you linked mentions aspirin. My dad used to take low dose aspirin occasionally but as far as I know he stopped. I wonder if it would have immediate impact or if its something you really have to take 10+ years to notice a difference at all? Any of you take low dose of aspirin?

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My dad takes simvastatin, forget the dose, but I think it's pretty standard (as in his cardiologist would approve of the dose). Dad's oncologist stated that the effects of the statin accumulate over time, so it is not something that would be make a difference immediately, but over time.

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Bud,

I have been taking a baby aspirin and Crestor every day for many years, but not sure it helps the PCa, which I am fairly new to (18 mo). The Crestor is a low dose, 10mg, and I am thinking of asking my cardiologist to up that.

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Garbonzeaux,

As I understand it, Rosuvastatin (Crestor) is relatively hydrophilic. You want to be taking a lipophilic statin like simsvastatin, atorvastatin, or lovastatin. I am not a physician or a pharmacist so I would suggest talking to an oncologist about the desirable statins to take in fighting Pca. This area is being actively investigated at this time so things may have changed.

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Good idea, Cal. Scheduled to meet with MO tomorrow. I'll bring it up.

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I talked to my MO about switching from Crestor to a lipophilic statin (based on literature for other types of cancer), and he said that I should definitely stay on Crestor because of recent research - we did not have enough time to get into the details unfortunately. Crestor (rosuvastatin) is one of the more effective statins for lowering cholesterol - so it is more efficacious on an equivalent dosage. A 10 mg dosage of Crestor is equivalent to 20 mg of simvastatin for example. Phil

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Your doctor's choice seems sound if you are focusing on cardiovascular health factors.

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I agree, since my LDL-C is elevated (due to ADT), but his recommendation was in the context of PCa - I did not mention that my LDL-C was high during our meeting. Phil

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I take one Simvastatin 10mg tablet every night before going to bed. So far I'm still dying...

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 01/09/2019 2:01 PM EST

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I take 40 mg of atorvastatin daily. It has had a positive effect on my cholesterol level (which is why my PCP prescribed it), But my prostate cancer, after having defeated all the standard therapies, is still going strong.

I did take a baby aspirin each day a few years ago but gave it up almost immediately as it was giving me uncontrollable nosebleeds.

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Are you taking Metformin or its natural bioequivalent Berberine root? Dr. Mark Scholz recommends both in his book "The Key to Prostate Cancer". Excellent read.

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Never heard of either. Not that that means much; the world is full of stuff I've never heard of. My cancer is super tough; it takes all the conventional treatments, chews them up and spits them out. So I'm only on lupron now, which isn't doing me a heck of a lot of good. Aside from the cancer I am in excellent health and always have been. The cancer is the only problem I have so I don't worry too much about other therapies.

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Please note that the second reference pertains to aspirin

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@PhilipSZacarias , thanks for catching this. I have updated the link at the top.

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