A Different Concept Of Immunotherapy

[Dayatatime]

Interesting read with a different spin on immunotherapy. There is more than one way to skin a cat and as long as we have these brilliant minds that stay the course eventually this case will get cracked.

vimm.it/prostate-cancer-the...

Ron

[pakb]

Interesting. Ater looking in to this it seems like my daughter, who has crohn's, and my husband may both benefit from this type of immunotherapy!

Sounds very promising.

[NPfisherman]

Thank you for the post, Ron...More information is always welcome....It seems that it is not just what our immune system doesn't do, but what it does do that keeps the beast going on inside us...perhaps, blocking IL-23 can prevent CrPC or in combination with one of the new experimental drugs like TAS3681 or TRC253, which are aimed at blocking AR mutation...hope they have an answer at some point, because progression is inevitable with the beast...

[Dayatatime in reply to NPfisherman]

I am not one bit surprised it was a young woman that discovered the ideology behind this theory. I think it's important to point out there is some serious talent working in this field and their generation is blessed with state of the art technology and very experienced mentors. They are determined and driven. Having 3 daughters, one working in the medical field, believe me when I say women will rule this world... I have been blessed with the proof! lol

[NPfisherman in reply to Dayatatime]

Absolutely... this young woman may have the answer to preventing castrate resistance...another brilliant researcher...they are using computers to design drugs to battle cancers...genomics is unlocking information to direct the attacks...the golden age of medicine is coming fast....there is a drug for dementia in phase III trials that blocks beta amyloid tangles from occurring, which could essentially freeze some dementia and prevent it from getting worse....amazing....

[Hidden]

I recently finished reading two books on immunotherapy (one was cancer specific, the other was general immunotherapy) "The Breakthrough: Immunotherapy and the Race to Cure Cancer by Charles Graeber and “The Beautiful Cure” by Daniel M. Davis. My husband is considering some Phase 1 immuno trials and I wanted to have a better understanding of the science because many MOs don't believe Provenge has much value. Someday they may get there but for every remission you hear on the news like Jimmy Carter, there are a whole lot of failures (even for people with the same cancer at the same stage). The body is so incredibly complex.

The thing I was going to mention is to be aware that treatments you have now may exclude you from near future trials that are more promising. Doing Provenge may keep you out of a trial like Dayatatime mentions. IMO, pause before trying something in the 2019 arsenal because "we don't know if it works but what does it hurt to try".

[j-o-h-n in reply to Hidden]

Jimmy and I have something in common (immunotherapy).... I'm taking Keytruda for my lung melanoma.... it's working...

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 01/06/2019 12:46 AM EST

[Dayatatime]

It is interesting for certain. I can't find a lot but here is another article I found on it.

cancertherapyadvisor.com/pr...

[Jbooml]

It’s so frustrating having a deadly disease progressing so far faster than conservative medical treatment testing allows...I’d love to know what the xtandi++ Gus is taking. I was joking with a friend visiting Nepal presently and mentioned that if he saw Enzalutamide on the pharmacy shelves in Kathmandu he please pick me up a gross....where the Indians produce it generically....he took it very seriously. Hi everybody I’m new to the forum...first post.

[Trecento in reply to Jbooml]

Yes, apparently they sell it under name of Bdenza in India - cheapest price I saw was almost 800 AUD a month - however how do you conduct due diligence? I know our onco wouldn't be happy for it to be sourced from there. And it is illegal, Astellas having the patent for some years hence.