Hi
I had an RRP in Dec 17 after PSA of 15, clear PSMA scan... resulting in pT3b with G7=4+3 and 5% tertiary 5 with lymphovascular invasion. Negative margins and undetectable micro PSA at six weeks looked good, but 0.024 at 5 months and now 0.56 at 9 months - it’s coming back.
Given the negative margins and SVI, I have been told the chances for eSRT actually curing me are probably around 10% at best, and probably not worth the risk. That fits with the nomogram at pcnrv.blogspot.com/2016/08/ so I have been looking at re-purposed drugs (Care Oncology) to try to slow progression while I figure out what to do.
So I was surprised to read replies by Canoehead and Schwab this morning that seem to suggest people are talking about “cure” in the context of PCa that’s more advanced than where i’m currently at.
It sounds like there is a more aggressive school of thought that I am not tapping into via my current Melbourne-based team - have I read this right, or am I confused?
When I have asked about ADT it has been explained as a holding pattern approach, something that might last years but that would eventually fail and lead to later stage approaches - but you seem to be talking about ADT, in combination with some other drugs, that only lasts a couple of years and may lead to a possible “cure”.... have I misunderstood you??? If this is in prospect for oligometastatic guys, presumably it may also work for someone like me, who presumably has micro-mets only at this stage?
I would greatly value any advice you may care to offer, thank you...
Stuart