Lynparza

[Craigslife]

My husband BRCA2 positive will begin treatment next week with Lynparza. Does anyone have experience taking this drug?

[vandy69]

Good Morning Craigslife,

I have been taking Lynparza since late October 2016, when the Guardant360 liquid biopsy found my cancer's ATM genetic defect.

Dr. Snuffy Myers prescribed 300mg twice a day, so I take 6 capsules in morning and another 6 in the evening. No discernible side effects.

Lynparza is very expensive, at just under $10,000/month retail price, so a prior authorization is required. I am covered under Humana's prescription drug plan (Medicare) and Lynparza is dispensed by Biologics to me on a monthly basis.

As to effectiveness, it is difficult to determine impact, as I also had proton beam radiation and take numerous other drugs.

Since I am in the fight, I appreciate any new therapies which may prolong life.

Never Give In!

Best wishes.

[Craigslife in reply to vandy69]

Vandy69,

Thank you for your response. Curious, has your PSA dropped while taking Lynparza? Craig's will begin with 400 mg twice a day.

Susan

[vandy69 in reply to Craigslife]

Hi Susan,

In the first month I saw no change. Did see declines in PSA for next few months, but I was also undergoing proton beam radiation at the same time, so impossible to determine cause.

For last 3 months, PSA is rising again, and I meet my new Med Onc on Tuesday to plan next steps.

As you have probably learned, everyone is unique in this battle, so Craig may have a completely different response.

I will celebrate 5 years with Stage 4 lymph node mets prostate cancer in August.

What is Craig's history?

Mark

[Craigslife in reply to vandy69]

Craig is 13 years stage 4. He has bone and lymph node mets. He was on zytiga for 3 1/2 years and when it started to fail switched to xtandi which did nothing. His PSA is 7 up from less than .1 a year ago. He had an RP in 2004, then 33 radiation treatment 3 years later. Then Lupron and provenge followed by zytiga and xtandi. We have had some great years since his diagnosis, and I am hoping for many more.

Susan

[podsart in reply to vandy69]

May I ask you who Dr Myers recommended you see after his retirement Nov1st?

[vandy69 in reply to podsart]

Dr. Myers referred me to Dr. Oliver Sartor of Tulane Medical School in New Orleans.

[podsart in reply to vandy69]

Thanks

Assume you live in that area of the country

[vandy69]

Live in Atlanta, but travel is not an issue. He referred a friend of mine who lives near us to a Med Onc in NYC. I think Dr. Myers is referring us to a particular doc who he thinks is best equipped for our type of cancer.

[rococo in reply to vandy69]

Can you give the name of med onc dr myers refered your friend to in new york city and if he is a pc specialist. Thank you. Rocco

[vandy69 in reply to rococo]

Good Morning Rococo,

Dr. Myers recommended Dr. Charles Drake, who I think is now at Columbia in NYC. My friend has had a bone met in his spine for years, but is having a wonderful response to Xtandi.

Best wishes.

[Sisira]

Take my curse also Nalakrats. Disgusting!

Sisira