Im looking for thoughts on bone mets for my husband. In 2006 diagnosed with PSA of 69.5 at age 49. Final Gleason after a radical surgery was 9/10. Post surgical PSA rose to .06 six months after surgery and they did 45 rounds of radiation to the pelvic region with Lupron. For the next five years or so PSA running at .01 with absolutely no fluctuation. Approximately 2011 PSA rose to .02 very slow rise up and down for the next few years. Never surpassing 1.50. In 2014 A mets was found in his clavicle with PSA still below 2. They radiated clavicle which Helped pain. Did not start any medication as his PSA still has remained @ 5 or below and fluctuates. After his last scan this month, he now has mets to pelvic region spine and ribs. Albeit small lesions. Clavicle has remained stable. With Mets to spine and rib the most recent, at same time his PSA dropped 2.6. Very confusing. He is in constant pain and has developed new symptoms urinating every hour at night, extreme fatigue, some loss of appetite, and a 20 pound weight loss. He did have a elective surgery in dec seemed to go downhill from there. His oncologist is relatively new to us about a year and a half. We discussed his going out on disability at this point because he is simply exhausted all the time. His doctors response which I found quite bizarre, was that he had no idea and did not believe that his symptoms were related to his bone metastases. Quite perplexing. When asked what he should do about the mets to the spine didn't have any answer. He said perhaps lupron but if you're tired now that will only make you more tired. Not crazy about this new doctor but now I'm even less so. He offered us no answers no treatment options and basically said he had no idea why he had those symptoms. He is also showing a string of cysts around his liver and in his kidneys. there was uptake to the parietal and zygomatic bones as well. Again no response from his onc on this. I'm really, really disturbed and not sure if we should find another onc or just assume that his condition is not as serious as it appears to me. Any thoughts in this would be much appreciated. Everyone in this site seems to know more than the doctors.