This might explain some of the new studies where taking Natural Anti-Inflammatories in combination with Chemo, Radiation or ADT made the treatments more effective. The idiots over here were telling us not to take these supplements with Chemo or Radiation because it might lessen ROS.
Nal, no wonder your Grandfathers Jewish Rye Bread Sandwich of garlic, hot peppers, onions, and turmeric worked.
Gus
Nal,
check out the supplement Zyflamend....lowers inflamation and study when zyflamend was stacked with Casodex results were better than either alone..I just bought some on Amazon....Zyflamend Whole Body Inflamation Response
Nal,
I will be able to monitor because my PSA is .1....in your case you should be able to keep <.1...as to dosage I plan on taking 3 caps per day spaced out and stacked with Casodex, Avodart, Metformin. Arimidex, and Cabergoline
Gus
Nal,
with any luck we will both make it to 100 and go fishing...maybe we should add your Grandfathers Super Jewish Rye Bread Sandwich
Gus
Nakakris, can you please provide a cite to the study or an abstract I can show to my med onc? I may have missed it, but did not see a cite in the article gusgold cited. Thanks.
Back in 2003, my academia-based research medical oncologist set a "working hypothesis that the transformation from an androgen-dependent to an androgen-independent phenotype is mediated by the expansion of an androgen-independent clone already present at the tine of androgen deprivation."
"If this model is correct, then it would be desirable to bring treatment to bear on the androgen-independent component when the corresponding tumor burden is minimal."
Translated to mean that androgen dependent and androgen independent cancer cells exist at the same time in the vascular and lymphatic systems as a mutated cell survival mechanism. Meaning that micro metastatic or microscopic residue cells can exist after primary treatment and if so, then chemotherapy very early with metastatic disease or adjunctive chemotherapy along with primary treatment before metastatic disease develops is warranted.
I was a subject of this hypothesis in 2004, today, my Stage 4 PCa is gone, mets resolved, and all scans clean, I remain undetectable despite ceasing hormonal injections seven years ago and commencement of small doses of T replacement two years later.
The Purpose of the Trial Study: Long-term hormonal ablation in prostate cancer is associated with decreased overall health and quality of life. Few reports emphasized the role of chemotherapy in the management of early stage prostate cancer. This study analyzed the safety and efficacy of androgen deprivation therapy (ADT) plus chemotherapy as initial treatment for patients identified as local failures or not eligible for prostatectomy or radiation therapy due to advanced disease presentation.
Results: Forty-six patients were enrolled, and forty-five patients were evaluable. Median progression-free survival (PFS) was 23.4 months. Median overall survival (OS) was 53.7 months. Out of 45 patients with measurable disease, 22 patients had an objective response: 9 patients achieved a complete response; 2 patients achieved a partial response; 10 patients achieved stable disease. Frequent grade 3 adverse events included elevated ALT (17 %), hypokalemia (13%), and hypophosphatemia (13 %). Grade 4 adverse events were rare and included low bicarbonate (2 %), hypokalemia (2 %), leukocytopenia (2%), and neutropenia (2%).
Do not fear chemo.
Gourd Dancer
Nal,
what is your opinion of this supplement -thinking of buying this and cutting out some individual supplements. Got my Zyflamend and ate a good breakfast and stacked 2 Zyflamend caps with 1 Casodex 50 mg
Gus
Where do (potential) future mets come from? Prostate? Or existing mets?
BSD 2000 hyperthermia treatment 
Chemo with docetaxel?
Finally, my MO's treatment plan:, no Triplet Therapy. Let's do Eligard, XTANDI, Radiation, XGEVA
Results from PSMA scan....... treatment options?
