My father was diagnosed about a month ago with advanced prostate cancer that has metastasized. English is not his first language and he is still absorbing all the information and its implications, so I am doing my best to research and communicate information. We are being treated at NYU Langone, where18 days ago he started lupron and two week ago his first cycle of taxotere+zometa+nuelasta. He is also taking casodex. Third-fifth day after chemo were bad but then he felt better; however around day nine he started having burning knee and foot pain. Last night and today he could hardly walk from the pain. Has anyone experienced this side effect before and know how to distinguish which drug is causing what?