I was diagnosed with WG in March 2010, can anybody enlighten me as to the difference between anca positive and anca negative.

[Kezzia]

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The Vasculitis UK Routemap at bit.ly/J8r9pz will provide you with a basic understanding of what this means plus there's a link to a more detailed scientific explanation at 1.usa.gov/MC7dSk

To be ANCA -ve requires a titre value of less than 1 in 20 and a PR3s score of less than 3. The old PR3 test was <7 so check when you receive your results.

Just a word of caution though. You can be ANCA -ve and have active disease and be very ill and vice versa. We have plenty of both within V-UK. Disease activity can't be reliably measured with an ANCA blood test alone and other markers & clinical symptoms need to be considered to diagnose what's actually going on.

Healthy wishes.