Hi, I am a 60 year old female and it was confirmed 2 years ago and I've been treated for MPA. I have now been told that it is in remission and I have been off medication now for 2 moths. However, since coming off my treatment, my knee joints are aching and I am wakened most nights with pain in my shoulders. I also have suffered a severe case of Shingles which has now left me with terrible nerve pain which I now take Pregabalin to try and control. I am not sure if this medication is causing depression but I feel so low at times. I work 24 hrs a week in an office but feel I can no longer work as trying to juggle work and doing housework is leaving me fatigued and no time for any pastimes. I often question myself thinking I am just lazy and beat myself up about it. I also have problems with my memory and cannot retain information very well unless I really concentrae. I wonder if anybody else feels this way and what they do to help themselves. I am considering resigning from my job but obviously financially it may not be possible but I feel I now need time for myself. What makes things worse is that I look well and my employer doesn't realises how fatigued I am and the pain I suffer with my joints and nerve pain, as I always try to remain smiling and try to do my job without messing up. Hope somebody here can give me some advise that can help me.