I have been on pred since 2011. I have been on maintenance dose of 5mg for over a year and reducing by .5mg every month. Had a really bad reaction last time they reduced me. So now 3weeks into the reduction. Last week I started feeling fatigued and put it down to a slight cold. However I now struggle to do the slightest thing. I am sleeping for 2hrs every afternoon and sleep ing through the night which I normal do not do! My question is can it take 2weeks for a reaction to the reduction? Sorry it was a bit long winded.