I currently take Accord and feel I am not well on these. I have had some helpful advice previously and wondered could I not take this tablet today to see if it is the cause of some of my symptoms?
I know I have to reinstate until I can obtain a different brand and talk to the GP, but I wondered if this would be okay to do for today so I can see if there is a change.
Thank you
Yes, good idea, going without for a day or two isn't generally a big issue as it'll take about a week for your fT4 to drop
Though it won't help with your already low fT3 issues which is going to cause you issues
Thank you for your reply. I usually take it at this time so will trial this for today. I do feel nervous about it though as I am sure I read it is important to not miss a dose, but it is helpful to have your advice that it shouldn’t make a difference.
Afraid I just don't agree with that.
Might be true for some, possibly most, but there's quite a number who notice within hours.
One trivial example, about once or twice a year I might inadvertently go to bed without taking my levothyroxine. Simply forgetting. Every time I simply don't get to sleep as usual. When I realise that I am not falling asleep, I think for a while, realise, get up and take it. And sleep well.
I haven't missed a dose for longer than a couple of hours in years except when deliberately delaying a dose due to a blood test. And those few hours do affect me.
Equally, some to notice within minutes when they take their tablets. As an observer, it is astonishing to see.
Fair enough 😏 I'm other end of the spectrum and can chop and change T4 without issue... perhaps wonky DIO2 at play? So many variables with all of us 😵
Another case of suck it and see 😁
Thank you for response and advice. We all have different experiences it seems but I have to say this has been the situation with me and I have felt the effect within an hour of taking my tablet which is why I woke up to thinking this today.
Could I ask if you have trialled the same thing or whether you just changed the brand you were taking? I see that you have done this more recently due to your responses to my previous posts.
Last time I took a different make for my 100 microgram dose, it felt like I'd taken nothing! And woke up feeling like that.
Immediately went back to my usual (for some time now) Aristo.
(I also top up that with 12.5 to 25 which does vary - currently Wockhardt. But have split Aristo and tried several other makes. Being only a small part of my dose, it doesn't make that much difference but am looking forward to Aristo launching their other doses.)
Interesting that the lactose in Wockhardt doesn't mess you up 🤔
I too take Vencamil lactose free (Aristo) like 🍄 but also T3 🤷♀️
I wonder if I am converting like I used to. Do you know if this can happen as you get older or happen due to other reasons?
I will try the new brand and see if t3 increases more. I do see an endocrinologist on occasions and might have to consider again with the issues I am having.
Certainly if you haven't got your proverbial ducks in a row conversion is effected so low ferritin, Vit D, Folate and B12 for starters which is why it is recommended here that everyone keep their levels up.... these tend to drop especially when under medicated
Some people find splitting the T4 dose can help?
Can you remember what brand you were taking in February? Also what other medication have you added since then as they could be the culprits?
Lansoprazole lowers stomach acid and others mention it affects absorption 😕
8 months ago your Vits and Mins looked ok'ish but if you haven't been supplementing will likely have dropped
Thank you for your response and help
I have stayed on the same brand of thyroxine since February. The only thing changed is my vitamin d tablet. I take doctors best and previously took a Vitabiotics one. Could this new one be affecting me in any way? My vitamin d was 65 in September and I have usually been okay on this level and found going higher than 90 was too high for me so I dropped down from Feb 23. I don’t take b vitamins or folate as I try to obtain from my diet. The endocrinologist I see said to only take if deficient as it can affect thyroxine absorption. I do take primrose oil but nothing else apart from vitamin d.
The anti acid I only took a few and then stopped and tried to cope with live yogurts and watching my diet (especially on the antibiotics). I may have to start these again but GP said to review in two weeks to see if infection settles.
I am using fucidin at present but I am not aware this can affect the thyroid in any way. Also, diazepam low dose only when needed and the same with propranolol.
Probably best to get your levels checked, usual recommendations to aim for above mid range, Vit D usually around 100...
I searched Propranolol and came up with this thread... healthunlocked.com/thyroidu...
Just missing one day will not tell you anything. One of the peculiar things about thyroid hormone replacement is that if you stop it, you suddenly feel much better and all your hypos symptoms will disappear. No-one knows why, but it happens with all forms of thyroid hormone replacement and in no way means that it's the THR that doesn't suit you. Sooner or later, all your symptoms will return. You would have to stay off it for about a month to get any idea about whether it's causing your symptoms, or if they're just exaggerated hypo symptoms - it often happens that symptoms get worse, or new symptoms appear when starting thyroid hormone replacement. So, you'd be causing yourself unnecessary anxiety for nothing. The only way to find out if it's the levo the culprit is to change brands and see if you feel better with different fillers in the pill.
So true GG, I was assuming Sailing is trying to discover if the tablet is causing rapid gastro distress.... her bigger issue is low fT3
Well, even if she is, I'm not convinced that's the best way to do it. One day is like the blink of an eye where thyroid is concerned. You can't prove anything in one day.
It's more a reaction to the excipients than thyroid... I certainly know about it if I take a tablet containing lactose 🤢💨
Yes, I realise that. Doubtful it would be to the T4 itself. But, even so. Is the OP lactose intolerant? I still doubt that just one day would prove anything. She might think it does, but...
I do have gastro distress but I have been on antibiotics that were strong. I have had an upset stomach since stopping so I am hoping this goes back to how it was before, although I do have to manage my diet to control this (ibs).
I also have low t3 like you said and it never used to be this low so maybe another brand will help this to rise again? The brand I am on though was okay at one point but I’m unsure if it is consistent or substandard at times through the batches (as previously mentioned).
Thank you again for your help.
Sorry I meant gastro distress not gastroscopy
My hubby is in the same boat as he had a leg ulcer and the antibiotics he was on have played havoc with his digestive system. Have you tried a course of probiotics or eating probiotic rich foods to help replace the good bacteria. Antibiotics are like napalm and strip everything away, both good and bad bacterias.
Yes I have been having live yogurt which does help. The chemist advised this also. Antibiotics do a lot of harm to the stomach I agree and it is a difficult balance when they are needed.
I don't think that would help. For 4 years I felt sometimes I'll and sometimes just a bit sicky on levo. I blamed the levo but I now know it was because I was undermedicated. In an effort to get well I all but stopped my levo for much longer than a day I have to admit. But when you stop levo you initially feel fantastic. Partly it's the relief and perception you've not taken what you feel is bad for you and partly because that is what happens when you first stop levo. How will you know that the feeling you have on that day isn't relief, psychological at not taking it?Also if some filler is causing you a problem and causing your gut or somewhere else not to work efficiently a day off won't be long enough for this problem to resolve so you will be none the wiser. Think about ingesting something that makes you come out in a rash. You stop eating that something for a day but the rash will remain for a while because it takes time to heal . This is what I mean.
Advice please
T3 advice please. 
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