I was chatting with my neighbour / friend last night and I recently learnt that his daughter 21 was diagnosed hypothyroid 3 years ago, I asked what meds she takes and he said Euthroid?
The family have lived in turkey until 2019 when the marriage broke down, his Turkish wife is a pharmacist in Turkey, not sure if this is relevant but worth a mention.
Interested in any information as when I googled I found ‘A New drug for thyroid replacement therapy’ not sure how old this article is pubmed.ncbi.nlm.nih.gov/414...
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Levo50
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Maybe there is a drug called Euthroid although I have never heard of it. Are you sure he did not say Euthyrox/Eutirox?Any new drug would still contain levothyroxine and/or liothyronine as thyroid hormone replacement is the only treatment for hypothyroidism.
Levo50, The article you've linked to is dated 1974. I'm guessing this is around the time when various brands of synthetic levothyroxine were first coming onto the market in different countries. Prior to this, most hypothyroid patients would have been treated with desiccated thyroid preparations.
From what I can see, the vast majority of occurrences of EUTHROID are typos/misspellings of EUTHYROID.
It was a combination medicine of levothyroxine and liothyronine in a 10:1 ratio - often referred to as Liotrix.
Generic Name
Liotrix
DrugBank Accession Number
DB01583
Background
Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion. It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients and combination hormone replacement therapy generally offers no therapeutic advantage. In fact, administration of T3 may result in supratherapeutic levels of T3.
AND
Euthroid (Parke, Davis (United States) (discontinued))
I wonder if that is the same as Thyrolar in the US which was also called Liotrix...? It has not been available for years. From the info above, it would seem it was discontinued because thyroid patients are not supposed to need T3, only T4.
Thank you for this detailed and informative reply, I did expect with the girls mother being a pharmacist in turkey would have done some research assuming she believes the addition of T3 would be beneficial (even if not necessary) - interesting, I will speak to the girl directly when she visits next to try get more detail.
There are several combination products. Most are either 4:1 - more or less emulating desiccated thyroid, or 10:1 more or less emulating the perception of the output of a healthy human thyroid.
I am very suspicious of much online information, as I frequently see equivalents identified where one falls into the first ratio camp, and the second into the other ratio camp.
That’s Helvella. I agree about skepticism re: online info. Can’t say I would want to jump in for a combination product anyway. But never say never. I just knew I’d seen it available at one of the online pharmacies I’d been using. Mind you, I have seen an awful lot of stuff available at these outlets and can’t say I’d want to try any of that either!
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