T3 side effect advice: Hello, I've just started... - Thyroid UK

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T3 side effect advice

jostafford0 profile image
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Hello, I've just started taking T3 (Tiromel) quarter of a 25mg tablet in the morning and I've started getting jittery with palpitations when I go to bed at night which is preventing me from sleeping. I know it is the T3 causing this and I also know I am very sensitive to medication. I also have the faulty DIO2 Homozygous gene.

My Endo reduced my Levo from 100mg to 75mg with the introduction of the T3.

Can anyone let me know if they had the same problems starting on T3 and whether it got any better? My foggy head in a morning has improved so I really want to give this a try.

Many thanks

Jo

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SlowDragon profile image
SlowDragonAdministrator

Is your T3 a 5mcg tablet or are you having to cut a 20mcg tablet into 1/4's?

You could try splitting the 5mcg into 2 x 2.5mcg with second 2.5mcg dose 8-12 hours after morning dose

(obviously easier if it's a 5mcg tablet)

Palpitations can be due to it being too long a gap between single T3 dose

As you are homozygous you're likely to need at least 3 x 5mcg eventually....but we often have to increase very slowly

I started T3 like this

Initially 2 x 1/8th of a 25mcg tablet (so approx 3mcg twice day) after about 10 days was able to increase to 2 x 6.25mcg

Held at this dose for 6-8 weeks before blood retest

I am Heterozygous DIO2. More on my profile

Are your vitamin levels optimal

jostafford0 profile image
jostafford0

Hi Slow Dragon, It’s a 25mcg tablet that I’m cutting into 4. It would be near impossible to cut the tablet any further than that but I’ll try. I bought this pack from a company abroad.

I tried adding another 1/4 in the afternoon the other day but it made my jitters & palpitations worse.

My vit & mineral levels are all ok - vit D 88 & B12 3 times over the normal limit (I self inject). Good levels of iron & folate. I supplement with magnesium & selenium too.

Jo x

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