When is best to take levothyroxine: Hi I’ve been... - Thyroid UK

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When is best to take levothyroxine

Helly_80 profile image
13 Replies

Hi I’ve been recently diagnosed with under active thyroid and starting on 50mcg which has been increased to 75mcg. I keep hearing mixed info on when to take the tablets and also whether other meds would interfere if taking them together can anyone help please?

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Helly_80 profile image
Helly_80
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13 Replies
Jake123- profile image
Jake123-

I findon't the best time to take it is in the morning without coffee tea or food an hour before and after it as it can integer with it working

bantam12 profile image
bantam12

The best time is what suits you, trial and error. I took mine in the morning for many years but decided to try night time and that works best for me.

Kes8 profile image
Kes8 in reply tobantam12

Totally agree. Started taking it in the morning then moved to bedtime as I was feeling nausea then moved it back to morning. Now settled at taking it anytime I wake up usually between 4 and 6am then that leaves a nice large gap before anything else.

Marz profile image
Marz

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Huzat profile image
Huzat

I felt a definite improvement when taking Levo last thing at night.

Article with links to trials on the subject.

verywellhealth.com/should-i...

Either way you should avoid taking with other meds.

Olliesmummy profile image
Olliesmummy

I always take mine in a morning, but recently a Dr told me to take them at Night. Also certain herbal meds you can't take with thyroid meds x

Peanut31 profile image
Peanut31

Hi

I take mine at 6am (set my Fitbit alarm on my wrist) then I have breakfast at 7.30am.

It’s advised other vitamins are taking 4 hours away from Levothyroxine.

Best wishes

Peanut31

MCP80 profile image
MCP80

It definitely is personal preference. I seem to get on better with taking mine at night at least 2-3 hours after you last had anything to eat or drink. It does need to be at least 4 hours away from most other tablets to ensure that they don't reduce the absorption. I would suggest if you are changing the time that you change it you give it a good few weeks to settle and see if it works for you as a couple of days etc isn't long enough for your system to settle into the change of time.

I used to take it in the morning & it didn't work with my funny shift pattern. I now take it at nighttime leave 4 to 5 hours after last meal ( takes that time for the stomach to empty). Just what suits you best though 🤔

I take mine in the morning at 6am and according to instructions I wait 30 minutes before having anything else. The instructions are on my prescription.

alexandra07 profile image
alexandra07

Sorry cant help Having problems myself Hope you get the right answer

Harper profile image
Harper

Hi. I have been taking thuroxine for 40 years. Mostly people say take it first thing in the morning on an empty stomach and it’s best not to eat or drink for about an hour after. This is what I do.

Best not to take it with other medication spread them out to avoid the thyroxine from not absorbing properly.

However some people do take it at night, I used to. It is trial and error.

I’m sure you will find how best suits you.

coppeen profile image
coppeen

I switched to taking it last thing at night over a year ago. Seems fine for me, I used to get an upset stomach every morning about an hour after taking it, I find this way I feel much better.

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