Month of birth is associated with the subsequent diagnosis of autoimmune hypothyroidism. A nationwide Danish register-based study.
Thvilum M1, Brandt F2, Brix TH1, Hegedüs L1 .
Author information:
1 Department of Endocrinology and Metabolism, Odense University Hospital, Denmark. Kloevervaenget 10, 6th floor, 5000, Denmark.
2 Department of Internal Medicine, Hospital of Southern Denmark, Sydvang 1, 6400, Sonderborg, Denmark.
Abstract
BACKGROUND:
The triggering of thyroid autoimmunity in the genetically susceptible remains a conundrum. Environmental exposures during gestation and/or early postnatally have proponents, as suggested in diabetes mellitus, with a higher incidence of births during spring and summer. Whether the development of autoimmune hypothyroidism (AIT) is influenced by month or season of birth is less clear.
METHOD:
Nationwide cohort study of 111,565 individuals diagnosed with AIT and four euthyroid controls per case, matched according to age and sex, were identified from Danish health registers. Differences in month-of-birth across the year was evaluated by the Walter-Elwood test. The risk of AIT patients being born in a certain month or season of the year was calculated using a Cox regression model.
RESULTS:
There was a significant difference in birth month between cases and controls, p<0.001. Individuals with AIT had a significantly increased risk of being born in June (Hazard ratio 1.04; 95% Confidence interval (CI): 1.02-1.08) and in the summer (June-August; HR 1.02; 95%CI: 1.01-1.04).
CONCLUSION:
In this large-scale nationwide cohort study, we found a higher risk of AIT when born in the summer season or more specifically in June, supporting the hypothesis that seasonal variations in exposures - gestationally and/or early postnatally - may contribute to the development of AIT. This article is protected by copyright. All rights reserved.
Me too.February 25 and I had a thyroid goitre that nearly killed me.Plus under hypthroidism before it was removed. I am on thyroxine for the rest of my life as a result.
I was end of April, my husband was end of January. We both have Hashimoto's. I worry about my 9 year old daughter (born end of May). She always seems tired and gets pins & needles a lot but hopefully I'm just being paranoid.
Check your daughters levels of B12 - Folate - Ferritin - VitD - from what I see with 5 grandchildren modern food does not always supply the best nutrients. Pins and needles can be linked to low B12 ....
Hi i did suffer from this 3 years ago thyroid under control now I was born in February but last week I just got diagnosed with osteoporosis and Osteoarthritis and checking online thyroid trouble is up there with these they are all linked xx
My two sisters were born in August and I was born in July. My niece was born in September, and my cousin was born in May. We all have autoimmune problems.
October for me, November for my son, December for my husband (no auto-immune), June for daughter (no auto-immune) and July for eldest son who has symptoms but is denying it.
I was born in April 1984. My doctor said my graves disease was a result of child birth. There is no history of thyroid problems in my family although my mum had part of her calcium gland, removed because it was producing too much calcium. The symptoms are quite similar to that of graves disease.
I'm going to go one further and say that it is looking like to me from the majority of answers to be more common with people from the cardinal signs cancer, Capricorn, aries and libra. I would think there would be a lot of virgos here too september, because Virgo rules the 6th house of health. There is a whole branch of astrology dedicated to medicine and health and I have personally found it to be very accurate for me. It goes right into cell salts and how the affects of transits can manifest in our health. I really like lyn koiners recommendations. She teaches medical astrology and has a lot of Information online. It's a s fascinating topic
I'm actually a Scorpio as born 27th October so I 'm not sure how that stacks up? I have multiple problems at present and though I can relate to lots of what I have read I'm also pretty confused about what is causing what. I'm so sorry, this is confusing for anyone so I will try to explain, I've been hypothyroid for a long time (years) & been taking 150Mcg thyroxine since day one, I can't remember when I last had a blood test & haven't a clue about all the different tests though when I read about gall bladder probs (had to have mine out) & tiredness (I have days which are 'cancelled') but I am also recovering from radio therapy and chemotherapy, going into the day surgery unit for facet joint jabs for osteoarthritis on 10th August, back at the dentist to get false teeth altered on Weds 2 nd August as still living on fortisip & want to eat and being driven crazy with both tinnitus & what I'm told is lymphatic tissue at the front of my neck which, some days makes me feel like a freak! Gosh, I am sorry for this outpouring but it's the first time I have actually said it (there is more but I think I have said enough for now). If anyone has some good but simple advice I would love to hear.........
I suggest you click on the green [ Write a post ] and put whatever you want help with there. That way, far more people will see it, and reply. It sounds like you need some support and many here will be happy to help as far as we can.
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