I've been taking meds for under active thyroid nearly a year now and they have not made one ounce of difference. I have had the dosage ammended higher 3 times and my weight gain has been ridiculous. I have been following healthy diets, exercising most days and using supplements but I only seem to be gaining more weight! Has anyone else had anything happen similar and overcome it? I'm getting beyond fed up with myself now and feel like I really need help!