50mcg is the usual starting dose with increments of 25mcg around every six to eight weeks until symptoms are relieved. We can also feel bad when starting levothyroxine, in fact I felt far worse than before I was diagnosd.
I didn't put on weight either although it is common amongst many.
PCOS is also a clinical symptom and I'll copy and paste an article and I don't have a link:
Multiple Ovarian Cysts as
a Major Symptom of Hypothyroidism
The case I describe below is of importance to women with polycystic ovaries. If
they have evidence, such as a high TSH, that conventional clinicians accept as evidence of hypothyroidism, they may fair well. But the TSH is not a valid gauge of a woman't tissue thyroid status. Because of this, she may fair best by adopting self-directed are. At any rate, for women with ovarian cysts, this case is one of extreme importance.
In 2008, doctors at the gynecology department in Gunma, Japan reported the case
of a 21-year-old women with primary hypothyroidism. Her doctor referred her to the
gynecology department because she had abdominal pain and her abdomen was distended up to the level of her navel.
At the gynecology clinic she underwent an abdominal ultrasound and CT scan. These
imaging procedures showed multiple cysts on both her right and her left ovary.
The woman's cholesterol level and liver function were increased. She also had a
high level of the muscle enzyme (creatine phosphokinase) that's often high in hypothyroidism. Blood testing also showed that the woman had primary hypothyroidism from autoimmune thyroiditis.
It is noteworthy that the young woman's ovarian cysts completely disappeared soon
after she began thyroid hormone therapy. Other researchers have reported girls with
primary hypothyroidism whose main health problems were ovarian cysts or precocious puberty. But this appears to be the first case in which a young adult female had ovarian cysts that resulted from autoimmune-induced hypothyroidism.
The researchers cautioned clinicians: "To avoid inadvertent surgery to remove an
ovarian tumor, it is essential that a patient with multiple ovarian cysts and hypothyroidism be properly managed, as the simple replacement of a thyroid hormone could resolve the ovarian cysts."
1. Kubota, K., Itho, M., Kishi, H., et al.: Primary hypothyroidism presenting as
multiple ovarian cysts in an adult woman: a case report. Gynecol. Endocrinol.,