Thyroid UK
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Starting levothyroxine today


I've picked up my first prescription for levothyroxine today, and am hopeful that after previous premature births and recurrent miscarriages that we are now going in the right direction.

I would like to take it tonight, rather than wait until the morning, but wondered how long I need to have waited after eating?

I am thinking of taking it at around 9 or 10pm tonight.

6 Replies

I would take it in the morning, (in case it keeps you awake) on an empty stomach about an hour before food.

Good luck


Chasing-Rainbows, Levothyroxine should be taken 1 hour before food and drink, or two hours after, two hours away from other medication and supplements, and 4 hours away from iron, calcium, vitaminD, B12 and oestrogen.

Research has demonstrated better results from taking Levothyroxine at night.

I hope you'll have your thyroid levels optimised in a few months and you have a successful pregnancy.


I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.


That's good to know. I'll make sure not to eat after 7-8pm then.

Fingers crossed, I'm really pleased with my new GP to have gotten the ball rolling at least.

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Hello firstly sorry for your loses i myself had a missed miscarriage in april they are truly devastating good luck with future pregnancies 💟

I take my levo at night i leave between 4 and 5 hours before taking my levo after eating i dont know if thats correct buts thats just what i do. What is your starting dose?


My starting dose is 50mcg. Sorry for your loss also. Thank you xx


Hopefully your GP will make sure your TSH is below 1 and your FT4 at the high end of the range. I am sorry for your losses, but now, hopefully the future will be brighter for you.

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