Thank you everyone for your replies and good wishes. After the initial 1st 2lb weight loss, I seem to just have stopped losing weight at all. I haven't lost a pound all week and i'm wondering if it is down to the beta blocker slowing down my heart rate. Don't get me wrong, I am over weight due to all my cancer meds, in particular the steroids that I was on during the last two summers and so the loss of weight is the least of my worries, but really I was trying to find out if it was normal to stop/start with the weight loss. My appetite is virtually zero, which I know contradicts normal symptoms of overactive thyroid, but again, this is probably down to the cancer meds. Truly speaking, it might be ironic and I definitely don't underestimate the seriousness of thyroid problems, but losing weight has been the first positive thing that has happened to me for the last couple of years and I was hoping that someone would tell me that it IS usual to stop/start and there is a possibility that I could lose more, at least until the doctors get my thyroid balanced. It would just be nice to feel a little more like myself. I suppose it's laughable that someone with my problems should worry about the way she looks but I'm sure anybody out there in my position would understand.