Harmonizing TSH Testing

[PR4NOW]

For those interested in the ongoing debate on TSH testing this article on the American Association of Clinical Chemists website should be of interest. There are some comments that relate to the UK. PR

aacc.org/publications/cln/2...

[LouiseRoberts]

Thanks for posting

x

[helvella Administrator]

The first conclusion:

until assay harmonization is implemented, assay-specific decision limits should be used in clinical practice guidelines and clinical studies;

is critical.

Every single person who wishes to challenge an interpretation of a guideline can point out that they have often been written without identifying the specific assay upon which they are based.

There are many reasons to disagree with TSH testing - this shows that even with the TSH camp all is very far from rosy.

Rod

[PR4NOW in reply to helvella]

Rod, it gets worse. You are familiar with Anderson et al in the JCEM, 2002, that was actually the fifth study done on the 'low index of individuality' of the TSH, T4 and T3 tests. The first study was done in 1987. I'm working on writing a piece but it will be after Xmas before it is finished. PR