Probiotics per definition should have beneficial effects on human health, and their consumption has tremendously increased in the last decades. In parallel, the amount of published material and claims for their beneficial efficacy soared continuously. Recently, multiple systemic reviews, meta-analyses, and expert opinions expressed criticism on their claimed effects and safety. The present review describes the dark side of the probiotics, in terms of problematic research design, incomplete reporting, lack of transparency, and under-reported safety. Highlighted are the potential virulent factors and the mode of action in the intestinal lumen, risking the physiological microbiome equilibrium. Finally, regulatory topics are discussed to lighten the heterogeneous guidelines applied worldwide. The shift in the scientific world towards a better understanding of the human microbiome, before consumption of the probiotic cargo, is highly endorsed. It is hoped that better knowledge will extend the probiotic repertoire, re-confirm efficacy or safety, establish their efficacy and substantiate their beneficial effects.
Scientific article: Brain fogginess (BF), gas and bloating: a link between SIBO, probiotics and metabolic acidosis
Background
D-lactic acidosis is characterized by brain fogginess (BF) and elevated D-lactate and occurs in short bowel syndrome. Whether it occurs in patients with an intact gut and unexplained gas and bloating is unknown. We aimed to determine if BF, gas and bloating is associated with D-lactic acidosis and small intestinal bacterial overgrowth (SIBO).
Also should be noted that extra caution needs to be taken when using the spore forming type (aka soil based probiotics)
Few years ago I decided to take acidophilus lactobacillus for constipation few months down the line voila got sibo the most awful thing ever , 2 weeks antibiotics sorted it out thank god x
Similar discomfort here. I've had all kind of examinations but nothing was to be seen. Only a microscopical minor small inflammation during/after colonoscopy. Now thinking about cecum / ascending colon problems due to bacterial overgrowth. Hope rifaximin will be of help but don't know if it will last. Have experiences with other types of antibiotics for different sicknesses. They helped but after discontinuing symptoms reocurred gradually, just like in your case. Even spoke with my gastroenterologist about cyclic courses of antibiotics.
I’ve had blood tests , ultrasound , ct scan all normal most of the pain is where the caecum is and ascending colon have not been constipated for months due to using laxatives but the pain remains I do take optifibre which has prebiotics and I do have gallstones whether that’s contributing I don’t know x
Ha ha yes this has crossed my mind too my first thought was a hernia as I get a pulling twisting feeling right side hurts to bend too ! What are your symtoms ? X
recurring abdominal discomfort / pain in right lower side of abdomen and sometimes also in my right side (lower) back if I don't mind what I eat. Constipation but at the moment due to chronic use of laxative I don't suffer that much from it, bubbling feeling/sound in the right lower quadrant, flatulence, bloating, severe chronic fatigue, very little mental and physical energy, weight loss, loss of muscle strenght and much more all over the body symptoms. Have had severe pain attacks in right lower area but luckily for the moment doing pretty well, no attacks.
Colonoscopy, MRI, CT, X-ray, blood and stool tests, colon transit time test. Even had surgery last year because of a Meckel's diverticulum. Was hoping this was causing my symptoms, than it would be 'solved', but it wasn't.
Wow I’ve read that constipation issues could be caused by not enough good bacteria in the gut , it’s frustrating when tests show nothing . Have you been tested for sibo ? And have you looked into ileocecal valve syndrome ? X
Not been tested for SIBO however based on the result of my experiences with antibiotics in the past for other problems and the results (didn't last however) I asked and was prescribed Rifaximin by my gastroenterologist . Not started yet with the course, some administrative issues to solve. Hope is that with a course of rifaximin a new eubyosis will be created in the intestines instead of what appears to be a dysbiosis at the moment and that it will last. Think that dysbiosis could compromise the Bauhin valve, the ileocaecal valve.
Hopefully it will get rid of it for you and it does seem the pain I get is the ikeocecal valve so I still could have some kind of bacterial thing going on there x
Vitamin supplements together with foods high in thiamine and other B vitamins could be one approach. Caution must be taken as certain beverage & food products such as tea, coffee, raw fish, and shellfish, contain thiaminases - enzymes that destroy thiamine. Using thiamine supplements that can pass more efficiently through the blood/brain barrier such as sulbutiamine or TTFD offer more saturation in the brain and body than thiamine hydrochloride. It's important to know the pros and cons of each form including another called benfotiamine. Magnesium is often deficient in stressful or painful conditions and it's also a component needed for thiamine to become bioactive. The krispin link offers magnesium information. The other links add to the roles of the wandering vagus nerve. Always consult with your health care provider before using any supplements.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Probiotics - trying different ones
Probiotic caused me diarrhea!
Pain...
