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Xtandi
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The Difficult Question most all of us will face.
Zolodex, Lupron, Casodex, Erleada,
Xtandi
, Zytiga w\predisone, now Docetaxel. We discussed the options again and how they could buy time or not. 1) Continue with Chemo but use Cabazitaxel instead: Cabazitaxel he said was more toxic and may be less tolerated than Docetaxel.
Zolodex, Lupron, Casodex, Erleada,
Xtandi
, Zytiga w\predisone, now Docetaxel. We discussed the options again and how they could buy time or not. 1) Continue with Chemo but use Cabazitaxel instead: Cabazitaxel he said was more toxic and may be less tolerated than Docetaxel.
dpowellnt
in
Advanced Prostate Cancer
4 years ago
Treatment after chemo - PARP inhibitor or immunotherapy trial?
I've taken
Xtandi
and Abiraterone. I had Provenge in 2016. I have discussed the next step with my MO at MD Anderson. One option is a PARP inhibitor.
I've taken
Xtandi
and Abiraterone. I had Provenge in 2016. I have discussed the next step with my MO at MD Anderson. One option is a PARP inhibitor.
WhiteStrat
in
Advanced Prostate Cancer
4 years ago
Xtandi+Keytruda may still work after Xtandi alone fails
In a small trial, 5 of 28 men (18%) got a PSA response (dropped at least by half) from the combination even after
Xtandi
alone failed. Median survival among responders was 42 months (some still alive at follow-up) vs 19 months for non-responders.
In a small trial, 5 of 28 men (18%) got a PSA response (dropped at least by half) from the combination even after
Xtandi
alone failed. Median survival among responders was 42 months (some still alive at follow-up) vs 19 months for non-responders.
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
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To state the obvious: early use of Zytiga or Xtandi extends survival in APC
. • Zytiga and
Xtandi
have been proven to add years of life in the mHSPC setting in some men, and months in the mCRPC setting, so avoiding those medicines [u]will reduce expected survival[/u]. • A recent study at Johns Hopkins showed that the t-SCNC subtype is less virulent than de novo SCNC https://
. • Zytiga and
Xtandi
have been proven to add years of life in the mHSPC setting in some men, and months in the mCRPC setting, so avoiding those medicines [u]will reduce expected survival[/u]. • A recent study at Johns Hopkins showed that the t-SCNC subtype is less virulent than de novo SCNC https://
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
APC doing end run on Docetaxel
I started second series.of docetaxel after Talapro2 trial began failing (
Xtandi
with talazoparib or placebo). Chemo round 1 brought psa from 20 to 9. Round 2, 9 to 4. Round 4 to 8. We did scan just before chemo and again last week. Progression is seen with new bone Mets.
I started second series.of docetaxel after Talapro2 trial began failing (
Xtandi
with talazoparib or placebo). Chemo round 1 brought psa from 20 to 9. Round 2, 9 to 4. Round 4 to 8. We did scan just before chemo and again last week. Progression is seen with new bone Mets.
Maleko808
in
Advanced Prostate Cancer
4 years ago
Keytruda
I have been at this fight for 6 years, Taxotere, casodex, lupron, xgeva,
Xtandi
. They all worked until they didn't. I am still on lupron and xgeva. I had my first infusion of Keytruda on July 2.
I have been at this fight for 6 years, Taxotere, casodex, lupron, xgeva,
Xtandi
. They all worked until they didn't. I am still on lupron and xgeva. I had my first infusion of Keytruda on July 2.
Jrb12
in
Advanced Prostate Cancer
4 years ago
AZD4635 with Xtandi
I am getting ready to start a clinical trial with AZD4635 and
Xtandi
. Just checking to see if anyone has participated in this clinical trial. If so how it has gone or is going for them.
Xtandi
alone did not work for me so I am hopi g the combination of the two will.
I am getting ready to start a clinical trial with AZD4635 and
Xtandi
. Just checking to see if anyone has participated in this clinical trial. If so how it has gone or is going for them.
Xtandi
alone did not work for me so I am hopi g the combination of the two will.
Hidden
in
Advanced Prostate Cancer
4 years ago
AZD4635 with Xtandi
Getting ready to do a clinical trial with AZD4635 and
Xtandi
. Just checking to see if anyone has did this clinical trial and if so how is it going.
Xtandi
alone did not work for me so hoping the combination of the two will.
Getting ready to do a clinical trial with AZD4635 and
Xtandi
. Just checking to see if anyone has did this clinical trial and if so how is it going.
Xtandi
alone did not work for me so hoping the combination of the two will.
Hidden
in
Fight Prostate Cancer
4 years ago
Xtandi added with Lupron
Oncol. now wants to add
xtandi
to his treatment plan. Haven't been on this site lately to know what is current protocol or next step. Can anyone offer suggestions. Hope all is well with this virus and otherwise. BOOGIE
Oncol. now wants to add
xtandi
to his treatment plan. Haven't been on this site lately to know what is current protocol or next step. Can anyone offer suggestions. Hope all is well with this virus and otherwise. BOOGIE
ROLNCIN1
in
Advanced Prostate Cancer
4 years ago
Low price Xtandi(Enzalutamide)
Today,I came across a news that generic version of enzalutamide has been launched in India by Zydus Cadila in the name of OBNYX 40 that costs around Rs. 25000 for a supply of 28 days,i.e, $340 approx. If any one is in need of the medicine please try to get it from India . May this information help those
Today,I came across a news that generic version of enzalutamide has been launched in India by Zydus Cadila in the name of OBNYX 40 that costs around Rs. 25000 for a supply of 28 days,i.e, $340 approx. If any one is in need of the medicine please try to get it from India . May this information help those
Vsahay
in
Advanced Prostate Cancer
4 years ago
Confused about treatment options
My urologist stated the
Xtandi
is probably doing some good also since my psa went to 12 then 19 considering I have 2 bone lesions on my hip.He said he would have expected the numbers to be higher if the
Xtandi
was not doing something.
My urologist stated the
Xtandi
is probably doing some good also since my psa went to 12 then 19 considering I have 2 bone lesions on my hip.He said he would have expected the numbers to be higher if the
Xtandi
was not doing something.
Scootman
in
Advanced Prostate Cancer
4 years ago
Zytiga Has Stopped. What's next
First is change to
Xtandi
. On average he has seen this work for only a couple of months but has have a couple of his patients do well. Second is chemo with either Taxtere or a platinum based drug. I'm Brac2 positive and he says there is evidence that Brac2 responds better to platinum drugs.
First is change to
Xtandi
. On average he has seen this work for only a couple of months but has have a couple of his patients do well. Second is chemo with either Taxtere or a platinum based drug. I'm Brac2 positive and he says there is evidence that Brac2 responds better to platinum drugs.
Newyork6264
in
Advanced Prostate Cancer
4 years ago
against the tide.....
On Lupron and
Xtandi
for a few years? Is is necessary...???? or could you just be "careful" and try not to break anything? and...while I am asking so many questions....LOL... "does anybody really know what time it is?" "The way to San Jose?" "where you're going to" etc. gJohn
On Lupron and
Xtandi
for a few years? Is is necessary...???? or could you just be "careful" and try not to break anything? and...while I am asking so many questions....LOL... "does anybody really know what time it is?" "The way to San Jose?" "where you're going to" etc. gJohn
greatjohn
in
Advanced Prostate Cancer
4 years ago
Roches. Aribiterone a risk at the moment
My husband has been taking
xtandi
but stopped due to side effects. Doc says he has to make decision whether to carry on with it or take aribiterone which will lower his immune system and could make him more susceptible to Covid. Has anybody got any advice .
Xtandi
made him very unwell Thanks
My husband has been taking
xtandi
but stopped due to side effects. Doc says he has to make decision whether to carry on with it or take aribiterone which will lower his immune system and could make him more susceptible to Covid. Has anybody got any advice .
Xtandi
made him very unwell Thanks
Roches
in
Advanced Prostate Cancer
4 years ago
.008 PSA Bicalutimide Monotherapy
I am not aware of a study that investigated mono therapy for example start with Bicalutimide then Zoladex, then add Zytiga, next
Xtandi
or some formula like this. The ones I saw all start with hormone therapy and then add something else.
I am not aware of a study that investigated mono therapy for example start with Bicalutimide then Zoladex, then add Zytiga, next
Xtandi
or some formula like this. The ones I saw all start with hormone therapy and then add something else.
Canuck53
in
Advanced Prostate Cancer
4 years ago
Is biopsy good from 2 years ago?
Now she wants to start him on
Xtandi
. I believe it is the same class of drugs and probably won’t work either. We continue to ask for gene sequencing. She now wants to use an old biopsy from two years ago.
Now she wants to start him on
Xtandi
. I believe it is the same class of drugs and probably won’t work either. We continue to ask for gene sequencing. She now wants to use an old biopsy from two years ago.
Faith1111
in
Advanced Prostate Cancer
4 years ago
Xofigo. What should I be aware of?
Looking for anyone's experience with Xofigo, and preferably with
Xtandi
. And feedback appreciated!
Looking for anyone's experience with Xofigo, and preferably with
Xtandi
. And feedback appreciated!
roke
in
Advanced Prostate Cancer
4 years ago
4th chemo session of docetaxal PSA increased from 2.7 to 4.4 to 9.3 in three consecutive sessions every 3rd week.
Has just approached I started with a rad prostectomy then 37 sessions of rad, Then zytiga 15 mos of bliss no rise in psa, then all good things end a jump up, then
xtandi
lasted two months. Then a L3 met zapped off Sept 2019 yay . But then a rapid 4 more came back on board.
Has just approached I started with a rad prostectomy then 37 sessions of rad, Then zytiga 15 mos of bliss no rise in psa, then all good things end a jump up, then
xtandi
lasted two months. Then a L3 met zapped off Sept 2019 yay . But then a rapid 4 more came back on board.
Costarica1961
in
Advanced Prostate Cancer
4 years ago
PSA levels rising, Oncologist says to consider alternatives
He is looking into Cosmic clinical trial to see if I qualify, and considering
Xtandi
, Taxotere, and Jevtana. I have tolerated Firmagon and Zytiga comparatively well, and feel good with plenty of energy. I would appreciate ideas, thoughts, and information.
He is looking into Cosmic clinical trial to see if I qualify, and considering
Xtandi
, Taxotere, and Jevtana. I have tolerated Firmagon and Zytiga comparatively well, and feel good with plenty of energy. I would appreciate ideas, thoughts, and information.
Philly13
in
Advanced Prostate Cancer
4 years ago
Bought time....I'll gladly pay you Tuesday for a hamburger today.
He had murmered "sweet nothings" in my ear of "undetectable" and "stopping Lupron" and "stopping
Xtandi
"........ now, in the morning after the fling of wild passion....he said to me...."you'll be on Lupron for the rest of your life".
He had murmered "sweet nothings" in my ear of "undetectable" and "stopping Lupron" and "stopping
Xtandi
"........ now, in the morning after the fling of wild passion....he said to me...."you'll be on Lupron for the rest of your life".
greatjohn
in
Advanced Prostate Cancer
4 years ago
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