Experiences with

Mitoxantrone

bones and it also reached his skull vault which is terrifying me a lot. he has already been on the following medicines over the last 4 years along with goserelin acetate implant shot every 3 months: -Bicalutamide -Abiraterone -Taxotere with and without Cisplatin -Enzalutamide -Paclitaxel + Carboplatin -Mitoxantrone

The remission-inducing arm consisted of cytarabine (3 g/m2 for younger patients or 1 g/m2 for patients over age 60) twice daily on days 1-3 plus 10 mitoxantrone mg/m2 on days 3-5 and subsequent alloHCT.

Has anyone used this for chemo? What is the likelihood of it helping where Docetaxel and Cabazitaxel did not work at all? Thank you

The IMPACT placebo group excluded patients with visceral metastases [6% of mitoxantrone group in the study by Berry et al. (21)] and enrolled 75.4% of patients with favorable Gleason scores.

his PSA is rising again and it reached 2.47 ng/mL, we're now torn in between: 1) his MO recommended Xtandi, which costs ~ 1300$ and that's around 4.5X of his monthly income and the national health service in Egypt is not administering it. 2)instead, the national health service suggested a mix of Mitoxantrone

Now, MO planned to start Inj Mitoxantrone. Can anyone help with the side effects or experience with Inj Mitoxantrone please ??

My oncologist indicates Other options including Provenge, xofigo , mitoxantrone, clinical trials. I'm adding the possibility of Lu-177 to the mix. We're all in this together! Keep Going!

of the mitoxantrone group (NEJM 351;15).

We reviewed that past this regimen the use of medications such as mitoxantrone certainly are possible but the evidence for efficacy in this type of setting is quite limited. We reviewed that lutetium is still under review by the FDA and the timing for approval remains uncertain.

Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376:1147-1154. Kantoff PW, Higano CS, Shore ND, et al.

(A good oncologist): "We can also consider changing Carboplatin to Cyclophosphamide or Mitoxantrone.

My Oncologist, Alexander Menter in Denver, is giving me these options: "I think Xofigo, carboplatin, Taxotere, mitoxantrone, and revisiting trials are all good options. " Any suggestions?

In the prospective, noninferiority, phase 3 trial PROSELICA, a dose of 20 mg per square meter maintained at least 50% of the survival benefit of a dose of 25 mg per square meter (which had been compared with mitoxantrone in the TROPIC trial) and was associated with a lower incidence of adverse events

Hello Has anyone out there been treated with Mitoxantrone chemotherapy an older drug?

This phase III study found an increased overall survival of 15.1 months in patients treated with cabazitaxel, compared with 12.7 months in men treated with mitoxantrone.[8] This was the first agent to demonstrate a survival benefit in docetaxel-refractory patients, and this trial led to the FDA approval

I have been through: Lupron continuous from beginning, Strive, Docetaxal, Xtandi, Radium 223, Cabazitaxel, Mitoxantrone and other radiation treatments for pain etc. Throughout the years I’ve been admitted to the hospital for adjustment to my pain meds a few times.

but then i had three consecutive increases and Abiraterone has now been stopped with my PSA at 5 So my question is i have been offered treatment that i can not find much information on here in the UK and was after your thoughts, so 20 sessions of RT to the prostate BAT testosterone flood and drought mitoxantrone

I have been through: Lupron continuous from beginning, Strive, Docetaxal, Xtandi, Radium 223, Cabazitaxel, Mitoxantrone and other radiation treatments for pain etc. You can go back and look at my prior post for better timeline.

Abstract Purpose In patients with metastatic castration-resistant prostate cancer (mCRPC), overall survival (OS) is significantly improved with cabazitaxel versus mitoxantrone after prior docetaxel treatment.

Just trying to find someone else who has tried Mitoxantrone [Novantrone]. Thanks. Jeanne