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Development of the world's first digital model of a cancer cell
The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research. Computer models have been standard tools
The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research. Computer models have been standard tools
2greys
in
Lung Conditions Community Forum
3 years ago
Confusion over vaccine efficacy for MPNS
I recognise that there is a huge difference between people with an MPN and those with
leukaemia
(for example). However, Blood Cancer UK have included MPNS as people who are likely to be in danger from COVID19 even after being fully vaccinated.
I recognise that there is a huge difference between people with an MPN and those with
leukaemia
(for example). However, Blood Cancer UK have included MPNS as people who are likely to be in danger from COVID19 even after being fully vaccinated.
amarylis
in
MPN Voice
3 years ago
Hyaluronic Acid and CLL
I have been using a Revitalift over the counter face serum that is 1.5% Hyaluronic Acid sold as a treatment for wrinkles and aging skin. I seem to remember somewhere that there is a tie to CLL. Does anyone have any info on this? TIA
I have been using a Revitalift over the counter face serum that is 1.5% Hyaluronic Acid sold as a treatment for wrinkles and aging skin. I seem to remember somewhere that there is a tie to CLL. Does anyone have any info on this? TIA
CBME
in
CLL Support
3 years ago
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Scientists identify 160 new drugs that could be repurposed against COVID-19
Cambridge scientists have identified 200 approved drugs predicted to work against COVID-19—of which only 40 are currently being tested in COVID-19 clinical trials. In a study published today in Science Advances, a team led by researchers at the University of Cambridge’s Milner Therapeutics Institute
Cambridge scientists have identified 200 approved drugs predicted to work against COVID-19—of which only 40 are currently being tested in COVID-19 clinical trials. In a study published today in Science Advances, a team led by researchers at the University of Cambridge’s Milner Therapeutics Institute
2greys
in
Lung Conditions Community Forum
3 years ago
What Factors Impact CLL Treatment Options? -- Patient Empowerment Network --Dr. Lyndsey Roeker is a hematologic oncologist at Memorial Sloan
What Factors Impact CLL Treatment Options? May 14, 2021 click to view video https://powerfulpatients.org/2021/05/14/what-factors-impact-cll-treatment-options/ What are the factors that impact chronic lymphocytic leukemia (CLL) treatment options? Dr. Lindsey Roeker notes important considerations that
What Factors Impact CLL Treatment Options? May 14, 2021 click to view video https://powerfulpatients.org/2021/05/14/what-factors-impact-cll-treatment-options/ What are the factors that impact chronic lymphocytic leukemia (CLL) treatment options? Dr. Lindsey Roeker notes important considerations that
lankisterguy
Volunteer
in
CLL Support
3 years ago
Nubie
Hello, I am new to this site. Although I was diagnosed with CLL 20 years ago. Currently receiving immunoglobulin infusions monthly
Hello, I am new to this site. Although I was diagnosed with CLL 20 years ago. Currently receiving immunoglobulin infusions monthly
Mother1943
in
CLL Support
3 years ago
Should you be minimizing your consumption of lipids?
For the scientific basis for minimizing lipids when you have CLL, see the following study: https://ashpublications.org/blood/article/132/Supplement%201/3117/263679/Chronic-Lymphocytic-
Leukaemia
-Relies-on-Lipid
For the scientific basis for minimizing lipids when you have CLL, see the following study: https://ashpublications.org/blood/article/132/Supplement%201/3117/263679/Chronic-Lymphocytic-
Leukaemia
-Relies-on-Lipid
HowardR
in
CLL Support
3 years ago
Frontline Ibrutinib/Venetoclax Elicits Durable Responses in CLL With Undetectable MRD
[i]
Fixed-duration ibrutinib plus venetoclax produced superior progression-free survival when compared with chlorambucil plus obinutuzumab in the frontline treatment of patients with chronic lymphocytic leukemia, with durable responses observed in those who achieved undetectable minimal residual
[i]
Fixed-duration ibrutinib plus venetoclax produced superior progression-free survival when compared with chlorambucil plus obinutuzumab in the frontline treatment of patients with chronic lymphocytic leukemia, with durable responses observed in those who achieved undetectable minimal residual
lankisterguy
Volunteer
in
CLL Support
3 years ago
Long-Term Data Showcase the Clinical Utility of Fixed-Duration Venetoclax/Obinutuzumab in Treatment-Naïve CLL
[i]
Fixed-duration venetoclax plus obinutuzumab demonstrated prolonged remissions compared with chemoimmunotherapy in elderly patients with previously untreated chronic lymphocytic leukemia and comorbidities.
presented by Othman Al-Sawaf, MD reported July 6, 2021 by Jessica Hergert https
[i]
Fixed-duration venetoclax plus obinutuzumab demonstrated prolonged remissions compared with chemoimmunotherapy in elderly patients with previously untreated chronic lymphocytic leukemia and comorbidities.
presented by Othman Al-Sawaf, MD reported July 6, 2021 by Jessica Hergert https
lankisterguy
Volunteer
in
CLL Support
3 years ago
UPDATE: WARWICK's ASCT Journey...
Mon Jun 28, 2021 9:18 pm Hello MPNers Since my last post I left hospital but after 10 days 5 days at my parents house till my kids got over sniffles and 5 days at home my liver function deranged significantly again so I was readmitted to Westmead Public Hospital. Today is day 22 of my stay back at hospital
Mon Jun 28, 2021 9:18 pm Hello MPNers Since my last post I left hospital but after 10 days 5 days at my parents house till my kids got over sniffles and 5 days at home my liver function deranged significantly again so I was readmitted to Westmead Public Hospital. Today is day 22 of my stay back at hospital
socrates_8
in
MPN Voice
3 years ago
Joint Committee on Vaccination and Immunisation (JCVI) advice on third primary dose vaccination
chronic leukaemias, and clinically aggressive lymphomas (including Hodgkin’s lymphoma) who were under treatment or within 12 months of achieving cure individuals under follow up for chronic lymphoproliferative disorders including haematological malignancies such as indolent lymphoma, chronic lymphoid
leukaemia
chronic leukaemias, and clinically aggressive lymphomas (including Hodgkin’s lymphoma) who were under treatment or within 12 months of achieving cure individuals under follow up for chronic lymphoproliferative disorders including haematological malignancies such as indolent lymphoma, chronic lymphoid
leukaemia
crashdoll
in
Lung Conditions Community Forum
3 years ago
New genetic research for CLL progression
https://www.hull.ac.uk/work-with-us/more/media-centre/news/2021/hull-york-medical-school-identifies-genetic-tendency-in-
leukaemia
-cells
https://www.hull.ac.uk/work-with-us/more/media-centre/news/2021/hull-york-medical-school-identifies-genetic-tendency-in-
leukaemia
-cells
deveritt
in
CLL Support
3 years ago
Doubling of absolute Lymphoctes
It has been 11 months now since I was diagnosed with CLL. Thereafter I have been tracking my WBC and Lymphocytes . The trend curve over a year is in the attached picture. I was also taking green tea extract , curcumin , vitamin C and D since being diagnosed. Until now did not experience any B symptoms
It has been 11 months now since I was diagnosed with CLL. Thereafter I have been tracking my WBC and Lymphocytes . The trend curve over a year is in the attached picture. I was also taking green tea extract , curcumin , vitamin C and D since being diagnosed. Until now did not experience any B symptoms
WilliamTan
in
CLL Support
3 years ago
Jakavi
I started Jakavi treatment some months ago as I was progressing from PV to myelofibrosis. I had immediate relief from itching but it seems to have returned. Enlsrged spleen, haematocrit down, platelets low and white cells not well controlled. What now?
I started Jakavi treatment some months ago as I was progressing from PV to myelofibrosis. I had immediate relief from itching but it seems to have returned. Enlsrged spleen, haematocrit down, platelets low and white cells not well controlled. What now?
lucieboo
in
MPN Voice
3 years ago
Functional Consequences of Mutations in Myeloproliferative Neoplasms
« Of great interest, a set of epigenetic mutations can co-exist with the phenotypic driver mutations in 35%–40% of MPNs. These epigenetic mutations, such as TET2, EZH2, ASXL1, or DNMT3A mutations, promote clonal hematopoiesis and increased fitness of aged hematopoietic stem cells in both clonal hematopoiesis
« Of great interest, a set of epigenetic mutations can co-exist with the phenotypic driver mutations in 35%–40% of MPNs. These epigenetic mutations, such as TET2, EZH2, ASXL1, or DNMT3A mutations, promote clonal hematopoiesis and increased fitness of aged hematopoietic stem cells in both clonal hematopoiesis
Manouche
in
MPN Voice
3 years ago
Last Call - Places available for today's UK CLL treatments update webinar
Once logged in head to
Leukaemia
Care's Facebook page at 3:30pm on 26th April and find the live video (it will be at the top of our feed). Please note, we will not be able to give individual medical advice.
Once logged in head to
Leukaemia
Care's Facebook page at 3:30pm on 26th April and find the live video (it will be at the top of our feed). Please note, we will not be able to give individual medical advice.
HAIRBEAR_UK
Founder Admin
in
CLL Support
3 years ago
Getting frustrated with the delay approval of ropeg In the US
Sometimes I can't help to think if enough is being done for MPN sufferers. According to multiple research ropeg has shown superiority over hydroxyurea with Ultimate possible significant molecular response in a selective number of MNP patients. So why there's a delay in getting access
Sometimes I can't help to think if enough is being done for MPN sufferers. According to multiple research ropeg has shown superiority over hydroxyurea with Ultimate possible significant molecular response in a selective number of MNP patients. So why there's a delay in getting access
markgenious1981
in
MPN Voice
3 years ago
Someone please answer this
My sister was diagnosed in October with cml after she said she needed some blood work done from feeling unwell. She has developed a mutation that is resistant to most treatments. She is going down hill. Someone please answer my question. 1 year prior to her Lukiema she randomly had both retinas detached
My sister was diagnosed in October with cml after she said she needed some blood work done from feeling unwell. She has developed a mutation that is resistant to most treatments. She is going down hill. Someone please answer my question. 1 year prior to her Lukiema she randomly had both retinas detached
Natweb76
in
Leukaemia Support
3 years ago
Bronchovascular lung markings / interstitial changes
I had the x-ray because I take a
leukaemia
drug that can cause pleural effusion. What could my x-ray report possibly mean? I have no symptoms. "Slightly coarsened bronchovascular lung markings / interstitial changes noted bilaterally mainly at the lung bases.
I had the x-ray because I take a
leukaemia
drug that can cause pleural effusion. What could my x-ray report possibly mean? I have no symptoms. "Slightly coarsened bronchovascular lung markings / interstitial changes noted bilaterally mainly at the lung bases.
British_Pluck
in
Lung Conditions Community Forum
3 years ago
Introduction of myself, PMF, from China
Hi, I'm Qi, from China, I'm 34 years old this year. I confirmed PMF in 2017. At that time, the splenomegaly was high, but it was not very high, and it was not so high all the time. These symptoms began to happen to me one after another as early as 2013. JAK2V617F gene mutation, there is only one mutation
Hi, I'm Qi, from China, I'm 34 years old this year. I confirmed PMF in 2017. At that time, the splenomegaly was high, but it was not very high, and it was not so high all the time. These symptoms began to happen to me one after another as early as 2013. JAK2V617F gene mutation, there is only one mutation
merlisa
in
MPN Voice
3 years ago
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