Search
Search
About
Log in
Join
Experiences with
Dopamine
Posts
Communities
2,068 public posts
Filter results
Stopping Azilect to change to Macuna? I need help.
So please, has anyone had success with macuna to increase
dopamine
and stop or reduce internal tremors and RLS? quote “Thus, for some, long-term use of
dopamine
agonists results in much worse RLS than before treatment, a condition referred to as RLS augmentation.
So please, has anyone had success with macuna to increase
dopamine
and stop or reduce internal tremors and RLS? quote “Thus, for some, long-term use of
dopamine
agonists results in much worse RLS than before treatment, a condition referred to as RLS augmentation.
Little_apple
in
Cure Parkinson's
1 year ago
Advice on non-medication treatment of RLS required
A neurologist I saw recently wanted to put me on
dopamine
-agonist patches which I refused, tho' I am following her recommended course of B12 injections. I've had 9 of the 12 jabs prescribed and I find my symptoms have been reduced to some extent and my sleep quality has been improved.
A neurologist I saw recently wanted to put me on
dopamine
-agonist patches which I refused, tho' I am following her recommended course of B12 injections. I've had 9 of the 12 jabs prescribed and I find my symptoms have been reduced to some extent and my sleep quality has been improved.
argyll1
in
Restless Legs Syndrome
7 months ago
NURR1
In particular, the team found that the naturally occurring molecule 5,6-dihydroxyindole (DHI), a
dopamine
metabolite, binds directly to and modulates the activity of Nurr1. https://parkinsonsnewstoday.com/news/new-parkinsons-strategy-targets-nurr1-protein/
In particular, the team found that the naturally occurring molecule 5,6-dihydroxyindole (DHI), a
dopamine
metabolite, binds directly to and modulates the activity of Nurr1. https://parkinsonsnewstoday.com/news/new-parkinsons-strategy-targets-nurr1-protein/
Little_apple
in
Cure Parkinson's
1 year ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
St. John’s wort, ursolic acid, Gardenia jasminoides
My guess is it’s because of his
dopamine
beta hydroxylase running fast, (genetic testing picked this up) breaking down the
dopamine
too fast so it runs out too quickly and causes rigidity and anxiety.
My guess is it’s because of his
dopamine
beta hydroxylase running fast, (genetic testing picked this up) breaking down the
dopamine
too fast so it runs out too quickly and causes rigidity and anxiety.
LAJ12345
in
Cure Parkinson's
1 year ago
IRL1117, Potential Improvement on Levodopa, May Enter Clinical Trial
IRLAB Therapeutics has selected a
dopamine
receptor agonist candidate called IRL1117 to advance as a Parkinson’s disease treatment, potentially as a longer-lasting alternative to levodopa with lesser side effects.
IRLAB Therapeutics has selected a
dopamine
receptor agonist candidate called IRL1117 to advance as a Parkinson’s disease treatment, potentially as a longer-lasting alternative to levodopa with lesser side effects.
Farooqji
in
Cure Parkinson's
1 year ago
Safinamide
3) trial a
dopamine
agonist (eg ropinerole) - am less keen on this course of action has anyone else had any experience that might help me better understand what options are the most likely to help.
3) trial a
dopamine
agonist (eg ropinerole) - am less keen on this course of action has anyone else had any experience that might help me better understand what options are the most likely to help.
Tomkins
in
Cure Parkinson's
1 year ago
Be careful with B6/P5P
It’s weird because I know b6 is vital in making
dopamine
, but too much is like not having enough.
It’s weird because I know b6 is vital in making
dopamine
, but too much is like not having enough.
38yroldmale
in
Cure Parkinson's
1 year ago
Anyone else have a Skin Biopsy?
Scan showed lowered
dopamine
levels. I had mild symptoms including. Bradykinesia, rigidity, masking and dystonia. primarily in the left foot.I don’t have visible tremors.yet . Didn’t respond well to C/L( lots of off time). . Symptoms have worsened.
Scan showed lowered
dopamine
levels. I had mild symptoms including. Bradykinesia, rigidity, masking and dystonia. primarily in the left foot.I don’t have visible tremors.yet . Didn’t respond well to C/L( lots of off time). . Symptoms have worsened.
BeachcomberFL
in
Cure Parkinson's
11 months ago
ChatGPT and Restless legs
Dopamine
agonists: These medications increase
dopamine
levels in the brain to reduce symptoms. Examples include pramipexole (Mirapex) and ropinirole (Requip). 2. Iron supplements: Iron deficiency can worsen restless leg syndrome symptoms, so iron supplements may be recommended. 3.
Dopamine
agonists: These medications increase
dopamine
levels in the brain to reduce symptoms. Examples include pramipexole (Mirapex) and ropinirole (Requip). 2. Iron supplements: Iron deficiency can worsen restless leg syndrome symptoms, so iron supplements may be recommended. 3.
thorp
in
Restless Legs Syndrome
1 year ago
PCPs take note
I am currently deeply affected by augmentation after too many years on
dopamine
agonists. I wish that a PCP had referred me to a specialist for treatment long before this augmentation began. I am now seeing a sleep medicine specialist.
I am currently deeply affected by augmentation after too many years on
dopamine
agonists. I wish that a PCP had referred me to a specialist for treatment long before this augmentation began. I am now seeing a sleep medicine specialist.
Perhapslove
in
Restless Legs Syndrome
1 year ago
Levodopa May Reduce Neuroinflammation
Summary: Levodopa, a drug commonly prescribed for the treatment of Parkinson’s disease that increases
dopamine
in the brain was found to reverse the effects of neuroinflammation on the reward system and improve symptoms associated with depression. https://neurosciencenews.com/levodopa-inflammation-depression
Summary: Levodopa, a drug commonly prescribed for the treatment of Parkinson’s disease that increases
dopamine
in the brain was found to reverse the effects of neuroinflammation on the reward system and improve symptoms associated with depression. https://neurosciencenews.com/levodopa-inflammation-depression
jimcaster
in
Cure Parkinson's
1 year ago
Neck and arm twitches at night leading to arm and leg spasms. Any treatment options?
Heat seems to help, but really keeping my
Dopamine
levels steady is the best. Anyone else have these, and what helps you reduce or eliminate them? Thanks.
Heat seems to help, but really keeping my
Dopamine
levels steady is the best. Anyone else have these, and what helps you reduce or eliminate them? Thanks.
Swimfast
in
Cure Parkinson's
1 year ago
Goat Weed - Neuroprotective
This activity, combined with its ability to improve neuronal energy metabolism and
dopamine
metabolism, has also shown promise in improving the symptoms of Parkinson’s disease.
This activity, combined with its ability to improve neuronal energy metabolism and
dopamine
metabolism, has also shown promise in improving the symptoms of Parkinson’s disease.
Gcf51
in
Cure Parkinson's
1 year ago
First patient receives milestone stem cell-based transplant for Parkinson Disease at Lund University, Sweden.
The transplantation product is generated from embryonic stem cells and functions to replace the
dopamine
nerve cells which are lost in the parkinsonian brain. This patient was the first of eight with Parkinson’s disease who will receive the transplant.
The transplantation product is generated from embryonic stem cells and functions to replace the
dopamine
nerve cells which are lost in the parkinsonian brain. This patient was the first of eight with Parkinson’s disease who will receive the transplant.
Hidden
in
Cure Parkinson's
1 year ago
04 am UK time
For those members going through the hell of
Dopamine
Augmentation reading this post must understandably feel that I’ve finally lost my wits or else found that silver bullet to rid the world of RLS. Well, I can honestly say that it’s neither, rather that I’ve reached a state of equilibrium.
For those members going through the hell of
Dopamine
Augmentation reading this post must understandably feel that I’ve finally lost my wits or else found that silver bullet to rid the world of RLS. Well, I can honestly say that it’s neither, rather that I’ve reached a state of equilibrium.
HipHop1972
in
Restless Legs Syndrome
1 year ago
Placebo vs Nocebo
But I seem to do well even if low on
dopamine
. I whine a lot about this. But I was Dx'd with MS then APS then a DVT then BPH then benign tumors in my liver then PD. I seem to have gotten over all of them but for the PD.
But I seem to do well even if low on
dopamine
. I whine a lot about this. But I was Dx'd with MS then APS then a DVT then BPH then benign tumors in my liver then PD. I seem to have gotten over all of them but for the PD.
kaypeeoh
in
Cure Parkinson's
1 year ago
S.Biomedics of Korea Okayed to test stem cell therapy for Parkinson’s disease
The study will evaluate the safety and efficacy of
dopamine
neural precursor cell transplantation therapy derived from homogeneous embryonic stem cells in patients who have been diagnosed with Parkinson's disease for more than five years.
The study will evaluate the safety and efficacy of
dopamine
neural precursor cell transplantation therapy derived from homogeneous embryonic stem cells in patients who have been diagnosed with Parkinson's disease for more than five years.
Farooqji
in
Cure Parkinson's
1 year ago
what do you do when you’re “off”
Someone recently told me that
dopamine
breaks down to noradrenaline and then to adrenaline, which can feel anxiety especially when movement is difficult. My tendency is to want to sit still until this passes, which can take what feels like forever. what do you do?
Someone recently told me that
dopamine
breaks down to noradrenaline and then to adrenaline, which can feel anxiety especially when movement is difficult. My tendency is to want to sit still until this passes, which can take what feels like forever. what do you do?
rebtar
in
Cure Parkinson's
1 year ago
SAM-e is it beneficial to Parkinson’s? It increases dopamine
Animal studies show that chronic SAMe administration increases dopaminergic tone in brain regions, including rat striatum (24), and increases CNS beta-adrenergic receptor density and activity (25,26). Thus, studies of central monoaminergic neurotransmitters support proposed mechanisms for SAMe antidepressant
Animal studies show that chronic SAMe administration increases dopaminergic tone in brain regions, including rat striatum (24), and increases CNS beta-adrenergic receptor density and activity (25,26). Thus, studies of central monoaminergic neurotransmitters support proposed mechanisms for SAMe antidepressant
Little_apple
in
Cure Parkinson's
1 year ago
Insulin Resistance, Parkinson's Disease, Consequences And What To Do About It
Levodopa works by converting into
dopamine
and replenishing the brain's reduced supply; straight
dopamine
has difficulty crossing the blood/brain barrier. Two, IR is thought to precede the development of T2D by 10 to 15 years.
Levodopa works by converting into
dopamine
and replenishing the brain's reduced supply; straight
dopamine
has difficulty crossing the blood/brain barrier. Two, IR is thought to precede the development of T2D by 10 to 15 years.
chartist
in
Cure Parkinson's
1 year ago
1
...
17
18
19
...
100
Next page
10
20
30
40
50
60
70
80
90
100
Filter results
Clear filters
Posted in
All communities
Cure Parkinson's
1098 results
Restless Legs Syndrome
600 results
CHADD's Adult ADHD Support
60 results
View top 10 communities
Sort by
Most Relevant
Newest