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Experiences with
Docetaxel
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Docetaxel
Anyone have any experience of this?
Anyone have any experience of this?
mundy
in
The Roy Castle Lung Cancer Foundation
3 years ago
the story continues...
Just completed 9th treatment with
Docetaxel
, PSA is still dropping , down from 3.58 to 2.3 in 21 days , am concerned about some potential COPD developing , shortness of breath and stamina are becoming a concern , I am not a smoker , besides the occasional cigar , but nothing gets inhaled , not sure
Just completed 9th treatment with
Docetaxel
, PSA is still dropping , down from 3.58 to 2.3 in 21 days , am concerned about some potential COPD developing , shortness of breath and stamina are becoming a concern , I am not a smoker , besides the occasional cigar , but nothing gets inhaled , not sure
Mollygrace666
in
Advanced Prostate Cancer
3 years ago
Psa rising
Chemo with
docetaxel
finished July 2019. Psa 0.085 after chemo. Started zytiga but lfts increased almost 10 fold. Changed to 250 mg with food and all labs good. Psa 0.08 8/10/20. Scan showed original Mets gone but uptake to left lesser trochanter, left shoulder and left posterior scapula.
Chemo with
docetaxel
finished July 2019. Psa 0.085 after chemo. Started zytiga but lfts increased almost 10 fold. Changed to 250 mg with food and all labs good. Psa 0.08 8/10/20. Scan showed original Mets gone but uptake to left lesser trochanter, left shoulder and left posterior scapula.
Altamontt
in
Advanced Prostate Cancer
3 years ago
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Docetaxel vs. Cabazitaxel--effectiveness?
If he's progressing after
docetaxel
what are the chances cabazitaxel will help? He's really reluctant to do more chemo as he has a lot of nausea and vomiting. Anyone here had success with cabazitaxel after failure of
docetaxel
?
If he's progressing after
docetaxel
what are the chances cabazitaxel will help? He's really reluctant to do more chemo as he has a lot of nausea and vomiting. Anyone here had success with cabazitaxel after failure of
docetaxel
?
WildRose6
in
Advanced Prostate Cancer
3 years ago
First Follow Up on MyTestosterone Trial
Elected 6 cycles of early
Docetaxel
, then SRT to prostate bed only, all in 2007. Intolerant/allergic to leuprolide so I did alternative ADT after BCR with bicalutamide 50mg plus dutasteride for 5 years before it failed. In 2019 I had Ga-68-PSMA scan showing only two PLNs in pelvis on left side.
Elected 6 cycles of early
Docetaxel
, then SRT to prostate bed only, all in 2007. Intolerant/allergic to leuprolide so I did alternative ADT after BCR with bicalutamide 50mg plus dutasteride for 5 years before it failed. In 2019 I had Ga-68-PSMA scan showing only two PLNs in pelvis on left side.
MateoBeach
in
Advanced Prostate Cancer
3 years ago
Intensifying ADT?
Reading up on a multitude of posts of the Forum, and looking at the Prostate Cancer news from 2017 about best options for newly diagnosed metastatic men, my impression as a relative newbie here is that amongst the best options are abiraterone/Zytiga or
Docetaxel
(however, I recall somewhere seeing the
Reading up on a multitude of posts of the Forum, and looking at the Prostate Cancer news from 2017 about best options for newly diagnosed metastatic men, my impression as a relative newbie here is that amongst the best options are abiraterone/Zytiga or
Docetaxel
(however, I recall somewhere seeing the
Purple-Bike
in
Advanced Prostate Cancer
3 years ago
What's next after my failure of ARV-110 trial
Am I missing out on having a proven effective treatment of Carboplatin + Taxane/
Docetaxel
chemo, since I am BRCA2+, by going on to another trial instead? Next trial is possibly AC225 + Xtandi + Keytruda combo therapy.
Am I missing out on having a proven effective treatment of Carboplatin + Taxane/
Docetaxel
chemo, since I am BRCA2+, by going on to another trial instead? Next trial is possibly AC225 + Xtandi + Keytruda combo therapy.
HopingForTheBest1
in
Advanced Prostate Cancer
3 years ago
Stage 4 initial recommendation Docetaxel and ADT
MD Anderson recommends
docetaxel
and ADT with primary site radiation after. I see there's some data of maintaining better control with early chemo, but wanted to know if anyone else has experienced it. My urologist recommended ADT and IMRT to all sites.
MD Anderson recommends
docetaxel
and ADT with primary site radiation after. I see there's some data of maintaining better control with early chemo, but wanted to know if anyone else has experienced it. My urologist recommended ADT and IMRT to all sites.
Vangogh1961
in
Advanced Prostate Cancer
3 years ago
NICE not playing nice again.
Though clinical trial evidence showed that study subjects taking Lynparza had improved progression-free survival and overall survival, NICE said that there is no direct comparison of Lynparza to the current standard of care for metastatic prostate cancer, which includes chemotherapy drugs
docetaxel
,
Though clinical trial evidence showed that study subjects taking Lynparza had improved progression-free survival and overall survival, NICE said that there is no direct comparison of Lynparza to the current standard of care for metastatic prostate cancer, which includes chemotherapy drugs
docetaxel
,
pjoshea13
in
Advanced Prostate Cancer
3 years ago
When to do a CT scan?
Here’s the recent background ( also see profile): Back in November I posted that my husband had completed 6 rounds of chemo (
docetaxel
)—concurrently he was receiving Eligard injections every 3 mos. and his PSA #s were coming down incrementally.
Here’s the recent background ( also see profile): Back in November I posted that my husband had completed 6 rounds of chemo (
docetaxel
)—concurrently he was receiving Eligard injections every 3 mos. and his PSA #s were coming down incrementally.
Lavender22
in
Advanced Prostate Cancer
3 years ago
Oral chemo
ModraDoc006/r given twice a day, once weekly was compared with 75 mg/m2 of intravenous
docetaxel
on a 21-day cycle.
ModraDoc006/r given twice a day, once weekly was compared with 75 mg/m2 of intravenous
docetaxel
on a 21-day cycle.
podsart
in
Advanced Prostate Cancer
3 years ago
Total combat
At my current state of knowledge this means combining ADT (transdermal estrogen) with chemo (Jevtana or
Docetaxel
) as well as Carboplatin, plus second-line hormonal therapy perhaps Zytiga plus a PARP inhibitor since I have a BRCA2 mutation. Possibly low-dose Bicalutamid too.
At my current state of knowledge this means combining ADT (transdermal estrogen) with chemo (Jevtana or
Docetaxel
) as well as Carboplatin, plus second-line hormonal therapy perhaps Zytiga plus a PARP inhibitor since I have a BRCA2 mutation. Possibly low-dose Bicalutamid too.
Purple-Bike
in
Advanced Prostate Cancer
3 years ago
The club you never wanted to join: Stage 4 Gleason 9+ at 46
After the Xtandi failed it was back to chemo, this time
docetaxel
. I also started some targeted high dose radiation on some bone mets to beat it back and help with bone pain. I did about 6-7 cycles of the
Docetaxel
then it failed and PSA started up again. So now it’s about 3 years later 2019.
After the Xtandi failed it was back to chemo, this time
docetaxel
. I also started some targeted high dose radiation on some bone mets to beat it back and help with bone pain. I did about 6-7 cycles of the
Docetaxel
then it failed and PSA started up again. So now it’s about 3 years later 2019.
Chugach
in
Prostate Cancer Under 60
3 years ago
good news
Blood work results prior to my 8th
docetaxel
injection this week were very good , PSA dropped again from 5.54 to 3.48 , shortness of breath is increasing so a check of the lungs is in order and a check of the old ticker , but feeling pretty good all things considered......
Blood work results prior to my 8th
docetaxel
injection this week were very good , PSA dropped again from 5.54 to 3.48 , shortness of breath is increasing so a check of the lungs is in order and a check of the old ticker , but feeling pretty good all things considered......
Mollygrace666
in
Advanced Prostate Cancer
3 years ago
Starting Chemo - Thoughts How To Manage Side Effects
I am starting
Docetaxel
on Tuesday. My Lupron plus Zytiga failed immediately. MO says this is the next best step. I so appreciate all of you sharing your personal experiences with all of us when we have questions. Please let me know any of your thoughts if you have time. Questions are: 1.
I am starting
Docetaxel
on Tuesday. My Lupron plus Zytiga failed immediately. MO says this is the next best step. I so appreciate all of you sharing your personal experiences with all of us when we have questions. Please let me know any of your thoughts if you have time. Questions are: 1.
Hidden
in
Advanced Prostate Cancer
3 years ago
Why continue LUPRON when ADT not working?
First therapy:
Docetaxel
with Lupron, then just Lupron for 1 year, 4months. Then added Abiraterone for 8 months. Currently stopping Abiraterone and I am having EBRT on femur. In three weeks I begin Radium 223.
First therapy:
Docetaxel
with Lupron, then just Lupron for 1 year, 4months. Then added Abiraterone for 8 months. Currently stopping Abiraterone and I am having EBRT on femur. In three weeks I begin Radium 223.
baltha
in
Advanced Prostate Cancer
3 years ago
Docetaxel not working
I have had 2
docetaxel
infusions so far with 3rd infusion scheduled this Thursday. Psa has increased from 120 to 174 and alk phos has increased from 590 to 617 since last infusion. Should I even go for 3rd infusion since
docetaxel
seems to be ineffective ?
I have had 2
docetaxel
infusions so far with 3rd infusion scheduled this Thursday. Psa has increased from 120 to 174 and alk phos has increased from 590 to 617 since last infusion. Should I even go for 3rd infusion since
docetaxel
seems to be ineffective ?
Peterd110
in
Advanced Prostate Cancer
3 years ago
Mum - second-line treatment
During the meeting it was agreed that mum would go on to
docetaxel
. I asked him about adding in nintedanib and, although he isn't convinced it will add much benefit, he has agreed to mum having it.
During the meeting it was agreed that mum would go on to
docetaxel
. I asked him about adding in nintedanib and, although he isn't convinced it will add much benefit, he has agreed to mum having it.
flatterycat
in
The Roy Castle Lung Cancer Foundation
3 years ago
Castrate resistant - new spot?
My dad is on Zoladex, he had had radiotherapy to the prostate and 4 x
Docetaxel
to treat his aPC last year. It should have been 6 x
Docetaxel
but it was cut short due to the Covid scare. With this, his PSA dropped to 1.1 (originally 44) in October, but January's PSA test bumped up to 7.2.
My dad is on Zoladex, he had had radiotherapy to the prostate and 4 x
Docetaxel
to treat his aPC last year. It should have been 6 x
Docetaxel
but it was cut short due to the Covid scare. With this, his PSA dropped to 1.1 (originally 44) in October, but January's PSA test bumped up to 7.2.
SC19
in
Advanced Prostate Cancer
3 years ago
New chemo
Now I am to have
Docetaxel
and Ninedanib Has anybody any stories to tell of this combination?
Now I am to have
Docetaxel
and Ninedanib Has anybody any stories to tell of this combination?
mundy
in
The Roy Castle Lung Cancer Foundation
3 years ago
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